| 白质DTI在急性一氧化碳中毒的临床应用 |
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| 引用本文： | 周玉荣,蒋涛,高敏,蒋珊珊,张勇.白质DTI在急性一氧化碳中毒的临床应用[J].影像诊断与介入放射学,2016(6):472-475. |
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| 作者姓名： | 周玉荣 蒋涛 高敏 蒋珊珊 张勇 |
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| 作者单位： | 1. 民航总医院放射科,北京,100123;2. 首都医科大学附属北京朝阳医院放射科,北京,100020 |
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| 摘 要： | 目的探讨磁共振扩散张量纤维束成像(DTI)参数FA和ADC值对急性一氧化碳中毒ACOP的诊断价值。方法 ACOP组56例,对照组21例。所有病例均行DTI检查,记录FA、ADC值,采用独立t检验进行统计学分析。结果 (1)ACOP患者组及对照组两侧膝部、放射冠FA、ADC值无差别(P0.05)。(2)FA值:ACOP患者组为0.7632±0.1206(胼胝体膝部)、0.3299±0.1029(放射冠额桥束),对照组为0.8329±0.0481(胼胝体膝部)、0.3800±0.1036(放射冠额桥束),P值分别为0.000、0.008(均小于0.05),差异有统计学意义。(3)ADC值:ACOP患者组为8.4594±1.5931(胼胝体膝部)、7.9261±1.1602(放射冠额桥束),对照组为7.8117±0.6160(胼胝体膝部)、7.3645±0.4879(放射冠额桥束),P值分别为0.000、0.000(均小于0.05),差异有统计学意义。结论 DTI可较准确反映ACOP患者白质区FA、ADC值变化,为早期诊断及治疗提供影像学信息。
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| 关 键 词： | 急性一氧化碳中毒 白质纤维束 扩散张量成像 |
Application of diffusion tensor imaging of white matter in acute carbon monoxide poisoning |
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| Abstract: | Objective To explore the application of apparent diffusion coefficient (ADC) and fractional anisotropy (FA) in acute carbon monoxide poisoning (ACOP).Methods Diffusion tensor imaging (DTI) was performed on patients with ACOP and healthy volunteers.The FA and ADC in the genu of the corpus callosum and fronto-pontine white matter tracts were compared by t-test.Results The FA of ACOP in the genu of the corpus callosum (0.7632±0.1206) and fronto-pontine white matter tracts (0.3299±0.1029) was significantly lower (P=0,0.008) than that of normal control (0.8329±0.0481,0.3800±0.1036).The ADC of ACOP in the genu of the corpus callosum (8.4594± 1.5930) and fronto-pontine white matter tracts (7.9261± 1.1602) was significantly higher (P=0) than that of normal control (7.8117±0.6160,7.3645±0.4879).Conclusion The FA and ADC on DTI reflect the white matter function of patients with ACOP for timely diagnosis and treatment. |
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| Keywords: | Carbon monoxide poisoning Magnetic resonance imaging Diffusion tensor MR imaging |
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