| HPLC法测定十五味龙胆花丸中龙胆苦苷和丁香酚 |
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| 引用本文： | 张妍,丁永辉,张晓萍,李玲莉,陈朝晖,杨锡. HPLC法测定十五味龙胆花丸中龙胆苦苷和丁香酚[J]. 中成药, 2011, 33(12): 2094-2097 |
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| 作者姓名： | 张妍 丁永辉 张晓萍 李玲莉 陈朝晖 杨锡 |
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| 作者单位： | 兰州大学药学院;甘肃省食品药品监督管理局;甘肃省中医学院;甘肃省食品药品检验所; |
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| 摘 要： | 目的建立十五味龙胆花丸(白花龙胆、檀香、诃子等)中龙胆苦苷和丁香酚的定量测定方法。方法采用ShiseidoC18色谱柱(250 mm×4.6 mm,5μm);甲醇-0.2%磷酸水溶液梯度洗脱为流动相;体积流量1 mL/min;柱温为室温;检测波长270 nm。结果龙胆苦苷和丁香酚质量浓度分别在0.141 4～1.060 8μg/mL(r=0.999 9)及0.156 6～1.174 8μg/mL(r=0.999 7)范围内与峰面积呈良好的线性关系;加样回收率(n=6)分别为99.85%(RSD为1.77%)和99.72%(RSD为1.85%)。结论方法简便可行、灵敏度高,可用于十五味龙胆花丸的质量控制。
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| 关 键 词： | 十五味龙胆花丸 高效液相色谱法 龙胆苦苷 丁香酚 |
Determination of gentiopicroside and eugenol in Shiwuwei Longdanhua Pill by HPLC |
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| ZHANG Yan,DING Yong-hui,ZHANG Xiao-ping,LI Ling-li,CHEN Zhao-hui,YANG Xi. Determination of gentiopicroside and eugenol in Shiwuwei Longdanhua Pill by HPLC[J]. Chinese Traditional Patent Medicine, 2011, 33(12): 2094-2097 |
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| Authors: | ZHANG Yan DING Yong-hui ZHANG Xiao-ping LI Ling-li CHEN Zhao-hui YANG Xi |
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| Affiliation: | ZHANG Yan1,DING Yong-hui2*,ZHANG Xiao-ping1,LI Ling-li3,CHEN Zhao-hui4,YANG Xi4(1.School of Pharmacy,Lanzhou University,Lanzhou 730000,China,2.Gansu Provincial Food and Drug Administration,3.Gansu College of Traditional Chinese Medicine,4.Gansu Provincial Institute for Food and Drug Control,China) |
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| Abstract: | |
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| Keywords: | Shiwuwei Longdanhua Pill HPLC gentiopicroside eugenol |
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