| RP-HPLC法测定橘红丸中甘草苷、柚皮苷、橙皮苷和迷迭香酸 |
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| 引用本文： | 谢强胜,王坤,尹宁宁.RP-HPLC法测定橘红丸中甘草苷、柚皮苷、橙皮苷和迷迭香酸[J].中成药,2011,33(12):2085-2088. |
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| 作者姓名： | 谢强胜 王坤 尹宁宁 |
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| 作者单位： | 山东省食品药品检验所; |
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| 摘 要： | 目的建立同时检测橘红丸(化橘红、陈皮、甘草、炒紫苏子等)中甘草苷、柚皮苷、橙皮苷和迷迭香酸的测定方法。方法采用RP-HPLC法。C18色谱柱;甲醇-0.3%磷酸水溶液为流动相;体积流量1.0 mL/min;检测波长284 nm。结果根据回归方程,4种成分线性范围分别为甘草苷2.16～64.8μg/mL,R2=0.999 6;柚皮苷7.59～227.7μg/mL,R2=0.999 2;橙皮苷7.54～226.62μg/mL,R2=0.999 5;迷迭香酸1.704～51.12μg/mL,R2=0.998 9。平均回收率分别为甘草苷102.1%,RSD 1.43%(n=6),柚皮苷100.8%,RSD 0.71%(n=6),橙皮苷98.7%,RSD 1.44%(n=6),迷迭香酸99.6%,RSD 0.82%(n=6)。结论该方法经济适用,操作简便、准确,重复性好,可用于橘红丸的质量控制。
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| 关 键 词： | 橘红丸 甘草苷 柚皮苷 橙皮苷 迷迭香酸 反相高效液相色谱 |
Determination of liquiritin,naringin,hesperidin,and rosmarinic acid in Juhong Pill by RP-HPLC |
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| XIE Qiang-sheng,WANG Kun,YIN Ning-ning.Determination of liquiritin,naringin,hesperidin,and rosmarinic acid in Juhong Pill by RP-HPLC[J].Chinese Traditional Patent Medicine,2011,33(12):2085-2088. |
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| Authors: | XIE Qiang-sheng WANG Kun YIN Ning-ning |
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| Institution: | XIE Qiang-sheng,WANG Kun,YIN Ning-ning(Shandong Provincial Institute for Food and Drug Control,Jinan 250101,China) |
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| Abstract: | AIM To develop a method for determining liquiritin,naringin,hesperidin,and rosmarinic acid in Juhong Pill(Citri grandis Exocarpium,Citri reticulatae Pericarpium,Glycyrrhizae Radix et Rhizoma,Perillae Fructus,etc.).METHODS The quantitative analysis was carried out on a column of Thermo Hypersil BDS C18 by RP-HPLC,by using a mobile phase of CH3OH-0.3% phosphoric acid under a flow rate of 1.0 mL/min.284 nm was selected as the detection wavelength.RESULTS The linear ranges of liquiritin,naringin,hesperidin,and ... |
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| Keywords: | Juhong Pill liquiritin naringin hesperidin rosmarinic acid RP-HPLC |
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