| 丹参生品及不同炮制品的体外抗菌活性研究 |
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| 引用本文： | 李昌勤,赵琳,杨宇婷,康文艺. 丹参生品及不同炮制品的体外抗菌活性研究[J]. 中成药, 2011, 33(11): 1948-1951 |
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| 作者姓名： | 李昌勤 赵琳 杨宇婷 康文艺 |
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| 作者单位： | 河南大学中药研究所; |
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| 摘 要： | 目的研究丹参不同炮制品(清炒、炒炭、米炒、酒炙和醋制丹参)的体外抗菌活性。方法采用纸片扩散法研究丹参不同炮制品对金黄色葡萄球菌(SA)、耐甲氧西林的金黄色葡萄球菌(MRSA)和β-内酰胺酶阳性金黄色葡萄球菌(ESBLs)的抑制活性。结果丹参生品及不同炮制品对SA和MRSA的抑制作用略强于ESBLs,对SA的抗菌效果最强;其中炒丹参的甲醇总提取物质量浓度在50 mg/mL对SA、MRSA、ESBLs的抑菌圈直径最大且相同;对相应样品的MIC值进行比较,显示各样品体外抗菌活性大小依次为:丹参生品及炮制品的甲醇提取物>石油醚和乙酸乙酯提取物>正丁醇提取物。结论本实验证明炒丹参和酒丹参的抗菌活性明显增强,而丹参炭的抗菌活性明显减弱,但仍具有一定的抗菌活性。
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| 关 键 词： | 丹参 丹参酮 炮制 抗菌活性 SA MRSA ESBLs |
Antimicrobial activity of Salvia miltiorrhiza and different processed products |
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| LI Chang-qin,ZHAO Lin,YANG Yu-ting,KANG Wen-yi. Antimicrobial activity of Salvia miltiorrhiza and different processed products[J]. Chinese Traditional Patent Medicine, 2011, 33(11): 1948-1951 |
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| Authors: | LI Chang-qin ZHAO Lin YANG Yu-ting KANG Wen-yi |
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| Affiliation: | LI Chang-qin,ZHAO Lin,YANG Yu-ting,KANG Wen-yi (Institute of Chinese Materia Medica,Henan University,Kaifeng 475004,China) |
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| Abstract: | AIM To study antimicrobial activity of Salvia miltiorrhiza and their decoction pieces,including simple stir-frying,carbonizing with stir-frying,stir-flying with rice,wine,and vinegar processed products.METHODS Disc Diffusion Methods were used to study antimicrobial activity against Staphylococcus aureus(SA),Methicillin-resistant Staphylococcus aureus(MRSA) and ESBLs of S.miltiorrhiza and decoction pieces.RESULTS The results showed that antimicrobial activity of tanshin decoction pieces against SA and MRSA w... |
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| Keywords: | Salvia miltiorrhiza Bge. tanshinone decoction pieces antimicrobial activity SA MRSA ESBLs |
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