| 中药消脓汤治疗术后腹腔感染的随机对照临床试验及成本-效果分析 |
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| 引用本文： | 王燕萍,李德榜,董春禄,李强. 中药消脓汤治疗术后腹腔感染的随机对照临床试验及成本-效果分析[J]. 中成药, 2011, 33(10): 1661-1663 |
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| 作者姓名： | 王燕萍 李德榜 董春禄 李强 |
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| 作者单位： | 兰州大学第一医院,甘肃兰州,730000 |
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| 摘 要： | 目的 评价中药消脓汤(大黄、连翘、黄芪和败酱草)治疗术后腹腔感染的安全性、有效性及经济性.方法 采用随机对照试验设计.选择腹腔手术术后感染病例60例,随机分为试验组(n=30)和对照组(n=30).试验组给予头孢哌酮他唑巴坦联合消脓汤治疗;对照组单纯给予抗菌药物治疗.疗程用至患者体温正常,症状消退后72 ～ 96 h.观察治疗前后症状、体征变化及不良反应,并进行血、尿、大便常规、肝肾功能及腹部B超检查.结果 经治疗后试验组显效25例,有效4例,无效1例;对照组显效24例,有效4例,无效2例,总有效率分别为83.30％、80.00％,两组比较差异无统计学意义(P＞0.05);试验组与对照组术后抗感染平均用药疗程分别为7.5、11.5 d,两组比较差异有统计学意义(P＜0.05).两组抗感染治疗成本分别为1455元和2093元,差异有统计学意义(P＜0.05).在用药过程中,未发现消脓汤的明显不良反应.结论 中药消脓汤联合抗菌药物治疗腹腔手术术后感染安全、有效、经济.
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| 关 键 词： | 消脓汤 术后腹腔感染 随机对照试验 成本-效果分析 |
The effect and cost-effectiveness of Xiaonong Decoction on the treatment for abdominal infection after operation |
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| WANG Yan-ping , LI De-bang , DONG Chun-lu , LI Qiang. The effect and cost-effectiveness of Xiaonong Decoction on the treatment for abdominal infection after operation[J]. Chinese Traditional Patent Medicine, 2011, 33(10): 1661-1663 |
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| Authors: | WANG Yan-ping LI De-bang DONG Chun-lu LI Qiang |
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| Affiliation: | WANG Yan-ping,LI De-bang,DONG Chun-lu,LI Qiang(The First Hospital of Lanzhou University,Lanzhou 730000,China) |
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| Abstract: | AIM To evaluate the effect and safety and cost-effectiveness of Xiaonong Decoction(Rhei Radix et Rhizoma,Forsythiae Fructus,Astragali Radix,Patriniae Herba) for abdominal infection after operation.METHODS In the retrospective study,60 patients with abdominal infection were randomly divided into trial group and control group.The method of cost-effectiveness was adopted to evaluate Xiaonong Decoction and Cefoperazone Sodium and Tazobactam Sodium.RESULTS These two groups were both efficient(the effective rate ... |
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| Keywords: | Xiaonong Decoction postoperative abdominal infection randomized controlled trials cost-effectiveness |
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