| 韶关市1190例手足口病病原体检测结果分析 |
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| 引用本文： | 马占忠,黄文波,何凤屏,谢秀萍,郭艳乐,刘玉兰.韶关市1190例手足口病病原体检测结果分析[J].现代医学仪器与应用,2013(1):30-31. |
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| 作者姓名： | 马占忠 黄文波 何凤屏 谢秀萍 郭艳乐 刘玉兰 |
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| 作者单位： | 汕头大学医学院附属粤北人民医院检验科;韶关学院医学院 |
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| 摘 要： | 目的分析韶关地区手足口病病原体分布情况。方法收集2011年1月～12月的1190例手足口病患者的咽拭子,采用实时荧光PCR方法检测肠道病毒71型(EV71)和柯萨奇病毒A组16型(CoxA16)。结果在1190份标本中病毒核酸阳性率为11.51%(137/1190),其中EV71占60.58%(83/137),CoxA16占39.42%(54/137);6月份高发,占29.08%(346/1190);男女比例为1.64:1,且0～4岁的患儿占93.11%。结论韶关地区2011年手足口病病原体以EV71为主,6月份高发,主要分布在0～4岁,男性多于女性,实时荧光PCR可用于手足口病病原体的检测,对手足口病的诊疗和防控具有重要意义。
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| 关 键 词： | 手足口病 肠道病毒71型 柯萨奇病毒A组16型 |
Analysis and pathogenic diagnosis of 1190 hand-foot-mouth disease in Shaoguan |
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| Authors: | MA Zhanzhong HUANG Wenbo HE Fengping XIE Xiuping GUO Yanle LIU Yulan |
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| Institution: | 1(1.Department of Clincal Laboratory,Yuebei People’s Hospital of Shantou University Medical College,Guangdong,Shaoguan 512026;2.Shaoguan Medical College,Guangdong,Shaoguan 512026) |
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| Abstract: | Objective To analyze the pathogenic diagnosis of the hand-foot-mouth disease(HFMD) in the city of Shaoguan.Methods Throat swab of 1190 HFMD patients were collected from January to December in 2011.Real-time PCR was used to detect enterovirus71(EV71) and CoxsackievirusA16(CoxA16).Results The positive rate of the virus nucleic acid was 11.51%(137/1190),EV71 was 60.58%(83/137),CoxA16 was 39.42%(54/137).The peak of HFMD infection ratio was 29.08%(346/1190)in June.Male to female ratio was 1.64:1,0～4 years old children accounted for 93.11%.Conclusions HFMD was mainly caused by EV71 in Shaoguan 2011.The peak of HFMD was in June and mainly distributed in 0～4 years old children.Male more than female.Real-time PCR can be used to pathogenic diagnosis of HFMD,which plays an important role in diagnosis,treatment,prevention and control of HFMD. |
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| Keywords: | Hand-foot-mouth disease Enterovirus71 CoxsackievirusA16 |
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