腓肠肌皮瓣联合负压封闭引流治疗胫骨慢性骨髓炎及软组织缺损

目的探讨腓肠肌皮瓣联合负压封闭引流,治疗胫骨慢性骨髓炎及软组织缺损的临床疗效。方法回顾分析2010年1月至2013年12月,20例胫骨慢性骨髓炎及软组织缺损患者,8例采用传统治疗方法 (对照组),12例采用腓肠肌皮瓣联合负压封闭引流治疗(实验组)。比较两组各项指标,包括治疗72 h后血清C反应蛋白变化率、治愈率、治愈所需时间、复发率等。结果实验组各指标均显著优于对照组(P<0.05):治疗72 h后血清C反应蛋白变化率、一次性治愈率明显高于对照组,治愈所需时间明显低于对照组,实验组复发率0%。结论腓肠肌皮瓣联合负压封闭引流治疗胫骨慢性骨髓炎及软组织缺损,疗效稳定、恢复快、复发率低,值得临床推广应用。

The Clinical Efficacy of Gastrocnemius Muscle Flap Combining with Vacuum Sealing Drainage in Treating Chronic Tibia Osteomyelitis with Soft Tissue Defect

Objective To explore the effect of gastrocnemius muscle flap combining vacuum sealing drainage （VSD） in the treatment of chronic osteomyelitis with soft tissue defect in tibia. Methods From Jan. 2010 to Dec. 2013, a total of 20 patients with chronic tibia osteomyelitis with soft tissue defect were analyzed retrospectively. The patients were divided into 2 groups, 8 cases were treated with traditional methods （control group） and other 12 cases were treated with gastrocnemius muscle flap combining VSD （experimental group）. Changing rate of CRP 72 hours post-operative, one-time cure rate, healing time and recurrence rate were assessed. Results All the indexes in experimental group were better than in control group （P＆lt;0.05）. Comparing with control group, the changing rate of CRP 72 hours post-operatively and one-time cure rate in experimental group were higher, while the healing time was lower. The recurrence rate of experimental group was 0%. Conclusion Gastrocnemius muscle flap combining with VSD is effective in treating chronic osteomyelitis with soft tissue defect in tibia with stable curative effect, quick recovery and low recurrence rate, and is worthy of promotion.