重症监护病房患者病原菌分布及耐药性分析 |
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引用本文: | 徐建利,;潘永梅. 重症监护病房患者病原菌分布及耐药性分析[J]. 医学检验与临床, 2014, 0(3): 26-28 |
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作者姓名: | 徐建利, 潘永梅 |
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作者单位: | [1]威海市立医院,山东威海264200; [2]文登市人民医院,山东文登264400 |
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摘 要: | 目的:调查重症监护病房(ICU)感染患者病原菌的分布及耐药情况,为临床合理选用抗菌药物提供依据。方法:采用VITEK-32全自动细菌鉴定系统及配套的GNI+、GNS-448和Etest、K-B纸片等方法对病原菌进行鉴定和药物敏感性试验。结果:526株病原菌分别来自呼吸道痰标本270株(51.5%)、血标本79株(15.0%)、尿标本61株(11.6%)、各种分泌物53株(10.1%)、脓液47株(8.9%)及16株其它标本(3.1%);分离率前5位的细菌分别为铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌、鲍曼不动杆菌和金黄色葡萄球菌。革兰阴性杆菌对亚胺培南、哌拉西林/他唑巴坦、丁胺卡那霉素和左氧氟沙星耐药率较低(均〈30.0%),革兰阳性球菌对万古霉素、利奈唑烷、替加环素及呋喃妥因等抗生素几乎完全敏感。结论:ICU感染患者病原菌种类较多,耐药率较高,临床医生应根据实验室药敏结果合理用药,减少耐药菌株的产生。
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关 键 词: | ICU 病原菌分布 耐药性 |
The distribution of pathogenic bacteria and drug resistance analysis in intensive care unit patients |
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Affiliation: | XU Jian-li, PAN Yong-mei (Weihai Municipal Hospital,Shandong Weihai, 264200) |
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Abstract: | Objective: To study the distribution and drug-resistance of pathogenic bacteria of patients in intensive care unit (ICU), and instruct clinical application of antibiotics reasonably.Methods:All specimens isolated and cultured from patients in our hospital were identified and analyzed by using the automatic microorganism analyzer VITEK-32, Etest and K-B.Results:A total of 526 isolates were recovered from clinical specimens of patients in intensive care units ( ICUs) , from 270 respiratory specimens ( 51.5%) , 79 blood specimens ( 15.0%) , 61 urinary specimens ( 11.6%), 53 secretion specimens ( 10.1%) , 47 pus specimens ( 8.9%) ,and 16 the others(3.1%) . The top 5 most common organisms isolated were Pseudomonas aeruginosa, Escherichia coli , Klebsiella pneumoniae, Acitetobacter baumannii and Staphylococcus aureus. The gram-negagive.Conclusions:The kind of pathogens and rate of drug resistance in ICU are high, and the clinical should use antibiotics reasonably to reduce the rate of drug resistance. |
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Keywords: | Intensive care unit The distribution of pathogens Drug resistance |
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