Abstract: | A total of 32 CHD patients with angina pectoris of effort, functional class I-IV, aged 46 to 68 were examined. Eight patients with cervical osteochondrosis of the same age were controls. In CHD patients with angina pectoris, functional class I-II, the content of leu-enkephalin in the blood plasma did not differ from that in the control group whereas in patients with angina pectoris, functional class II-IV, it was lowered by 42%. In CHD patients aged 46 to 55 the level of leu-enkephalin in the blood plasma was raised, in the group of patients aged 55 to 68 it was considerably lowered. |