原发性虹膜睫状体囊肿与前房角变化对应关系的研究

目的 探讨原发性虹膜睫状体囊肿的大小、分布特征及其与相应部位前房角变化的关系.方法 横断面观察性病例研究.在本院眼科行常规体检的人群中,若发现浅前房,进一步行UBM检查.对UBM检查中发现有虹膜睫状体囊肿的患者,记录其囊肿数量、大小、眼别、部位和象限,比较UBM图像上囊肿所在部位的前房角形态与非囊肿部位的前房角形态,观察并记录前房角是否变窄或关闭,分析囊肿导致相应前房角变窄或关闭的相关因素.分别采用t检验、X2检验和直线相关分析对数据进行统计.结果 在457例受检者(914只眼)中,发现有囊肿的患者134例(200只眼),占被检人数的29.32%,均为原发性虹膜睫状体囊肿.共检出囊肿502个,其中41.24%(207/502)位于虹膜睫状沟,58.37%(293/502)位于睫状冠;44.22%(222/502)位于颞下象限,26.88%(135/502)位于鼻下象限,23.11%(116/502)位于颞上象限,5.38%(27/502)位于鼻上象限.囊肿的平均大小为(0.6289±0.2329)mm,中囊肿占86.05%(432/502).虹膜睫状沟囊肿导致相应部位前房角变窄或关闭的发生率为82.13%(170/207),睫状冠囊肿导致相应部位前房角变窄或关闭的发生率为22.87%(67/293),二者差异有统计学意义(X2=170.83,P<0.01).囊肿大小导致相应前房角变窄或关闭的比例值,行直线相关分析,二者呈正相关(r=0.9939,P<0.01).结论 正常人群中原发性虹膜睫状体囊肿的发病比例高,部分囊肿可导致前房角变窄或关闭;囊肿的部位和大小是导致相应部位的前房角变窄或关闭的相关因素.

Primary iris-ciliary body cyst and its relevancy with the change of anterior chamber angle

Objective To investigate the characteristics of the size and distribution of primary iris-ciliary body cysts and its associated with the change of anterior chamber angle. Methods It was a cross sectional study. Patients with shallow anterior chambers found in routine health examinations were evaluated with UBM scan. Any primary iris-ciliary body cysts detected were recorded in the parameters of quantity, size,location, and quadrant. The shape of the angle in the UBM was compared to the surrounding area of angle without the cyst, and also whether the angle was narrowed or closed was recorded. The factors related to the corresponding narrowed or closed angle were analyzed. Results The 502 cysts were detected in 134 (29.32%)of the 457 patients,which were all primary iris-ciliary body cysts. The cysts were located in the iridociliary sulcus (41.24%) and pars plicata (58.37%) and distributions were 44.22% situated at the inferotemporal quadrant,26.88% at the inferonasal quadrant,23.11% at the superotemporal quadrant and 5.38% at the superonasal quadrant. The largest base size of the cysts was 0.6289±0.2329 mm and most were mid-sized cysts (86.05%). The incidence of the cysts with corresponding chamber angle narrowing or closure in the iridociliary sulcus was 82.13% (170/207) ,and in the pars plicata was 22.87% (67/293). The difference between them was statistical significant(X2 = 170.83 ,P <0.01). The relationship between the cyst size and the proportion of the cysts which caused corresponding angles narrowing or closure was analyzed by way of rectilinear correlation, and it was found to be a positive correlation (r= 0.9939, P< 0.01). Conclusions The incidence of primary iris-ciliary body cysts in the normal population is high and some may cause corresponding angle narrowing or closure; The location and size of the cysts are the factors to induce narrowing or closure of the angle in the corresponding area.