| 戊四唑点燃大鼠海马、杏仁核一氧化氮合酶阳性神经元的变化 |
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| 引用本文： | 李春香,王海燕,等.戊四唑点燃大鼠海马、杏仁核一氧化氮合酶阳性神经元的变化[J].黑龙江医药科学,1999,22(5):3-3. |
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| 作者姓名： | 李春香 王海燕 |
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| 作者单位： | 佳木斯大学医学院儿科教研室 |
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| 摘 要： | 目的：探讨一氧化氮（NO）在戊四唑（PTZ）点燃发病机理中的作用，方法：每天注射PTZ建立大鼠点燃模型，运用组织化学方法观察海马，杏仁核一氧化氮合酶（NOS）阳性神经元变化，结果：点燃后海马，杏仁核内NOS阳性神经元明显增多，结论：NO促进了戊四唑点燃的形成。
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| 关 键 词： | 戊四唑 点燃 一氧化氮合酶 一氧化氮 抗癫痫药物 |
Alteration in NOS positive neurons in hippocampus and amygdala of rats kindled by pentylenetetrazol |
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| Li Chunxiang et al.Alteration in NOS positive neurons in hippocampus and amygdala of rats kindled by pentylenetetrazol[J].Heilongjiang Medicine and Pharmacy,1999,22(5):3-3. |
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| Authors: | Li Chunxiang |
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| Institution: | Li Chunxiang et al |
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| Abstract: | Aim:To explore the pathogenetic role of nitric oxide in pentylenetetraZol (PTZ)- kindling. Methods: The rat kindling model was induced by daily injection of PTZ. Wc observed the alteraion in NOS positive neurons in the rat hippocampus and amygdala of by biochemical methods.Results: The NOS positive neurons in the rat hippocampus and amygdala after kindling were increased significantly. Conclution:NO might promote the formation of kindling by PTZ. |
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| Keywords: | pentylenetetrazol kindling nitric oxide synthase nitric oxide |
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