| 一氧化氮合酶抑制剂与脑缺血 |
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| 引用本文： | 胡苗苗,李运曼. 一氧化氮合酶抑制剂与脑缺血[J]. 中国临床药理学与治疗学, 2006, 11(1): 10-13 |
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| 作者姓名： | 胡苗苗 李运曼 |
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| 作者单位： | 中国药科大学生理教研室,南京,210009,江苏 |
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| 摘 要： | 随着对一氧化氮、一氧化氮合酶在脑缺血中作用的深入研究，一氧化氮合酶抑制剂也在不断被开发，并成为保护缺血脑损伤的热点研究之一。本文综述了一氧化氮合酶抑制剂尤其是nNOS和iNOS抑制剂在脑缺血损伤中的作用，为缺血性脑损伤疾病的治疗提供新的途径。
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| 关 键 词： | 一氧化氮 一氧化氮合酶 一氧化氮合酶抑制剂 脑缺血 |
| 文章编号： | 1009-2501(2006)01-0010-04 |
| 收稿时间： | 2005-10-31 |
| 修稿时间： | 2005-12-10 |
Nitric oxide synthase inhibitors and cerebral ischemia |
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| HU Miao-miao,LI Yun-man. Nitric oxide synthase inhibitors and cerebral ischemia[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2006, 11(1): 10-13 |
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| Authors: | HU Miao-miao LI Yun-man |
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| Affiliation: | Department of Physiology, China Pharmaceutical University, Nanjing 210009, Jiangsu , China |
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| Abstract: | As the effects of the nitric oxide and nitric oxide synthase have been investigated a lot, the nitric oxide synthase inhibitors were widely explored and become one of the highlights in the cerebral ischemia research. This paper reviewed the effects of nitric oxide synthase inhibitors especially the nNOS inhibitors and iNOS inhibi- tors on the cerebral ischemia damage. |
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| Keywords: | nitric oxide nitric oxide synthase nitric oxide synthase inhibitors cerebral ischemia |
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