Antisocial Personality Disorder and Alcohol-Induced Aggression |
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Authors: | F. Gerard Moeller Donald M. Dougherty Scott D. Lane Joel L. Steinberg Don R. Cherek |
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Affiliation: | Psychopharmacology Laboratory, Department of Psychiatry and Behavioral Sciences, University of Texas-Houston, Health Science Center, Houston, Texas. |
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Abstract: | This study compared the effects of alcohol on aggressive responding between subjects with antisocial personality disorder (ASPD) and subjects without ASPD. Eighteen alcohol drinking subjects (10 subjects without ASPD and 8 subjects with ASPD) underwent testing on a laboratory measure of aggression, the Point Subtraction Aggression Paradigm, after consumption of placebo and three doses of alcohol (0.25 g/kg, 0.5 g/kg, and 1.0 g/kg). There was a significant difference in the effect of alcohol on aggressive responding on the Point Subtraction Aggression Paradigm between subjects with ASPD and subjects without ASPD. Subjects with ASPD had a greater increase in aggressive responding after alcohol, compared with non-ASPD subjects. There was no difference between the two groups in the effect of alcohol on monetary-reinforced responding. |
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Keywords: | Alcohol Aggression Antisocial Personality Disorder |
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