胶体金法检测梅毒特异性抗体

目的：探讨梅毒螺旋体特异性抗体胶体金法（TPAb)对梅毒诊断的实用性和优越性。方法：用TPAb法对梅毒患者，非梅毒患者血清进行检测，同时与快速血浆反应素试验（RPR）和梅毒螺旋体血凝试验（TPHA）相比较。结果：TPAb法检测一期梅毒21例敏感性为71.43%，高于RPR法（57.14%)及TPHA法（66.67%)；二期梅毒64例，TPAb法及TPHA法检测敏感性均为100%，高于RPR法（92.19%)，同时对125例非梅毒患者血清进行了检测，结果全部阴性，特异性为100%。结论：TPAb法具有较高敏感性和特异性而且简单、方便、快速，适用于各期梅毒的诊断。

Detection of specific antibody ofT/reponema pallidum by colloidal gold

Objectives: To determine the applicability and superiority of TPAb assay in the diagnosis of syphilis.Methods:TPAb was used to detect the specific antibody of syphilis in serum from syphilis and non syphilis patients and compared with RPR and TPHA. Results: In 21 primary syphilis patients, the sensitivity of TPAb, TPHA and RPR was 71.43%, 66.67% and 57.14%, respectively. In 64 secondary syphilis patients, the sensitivity of TPAb, TPHA and RPR was 100%, 100% and 92.19%, respectively. In 125 non syphilis patients, the specificity of TPAb was 100%. Conclusion : TPAb is a sensitive, specific, simple and rapid method, which can be used in syphilis diagnosis.