2002～2005年烧伤整形病房感染病原菌的分布和药敏分析

目的:对我院烧伤整形病房感染的病原细菌分布及药敏情况进行分析为临床选药提供参考。方法:回顾分析2002年~2005年间我院烧伤整形病房住院患者感染及药敏情况,细菌的鉴定及药敏采用MicroscanWalka-way40全自动系统。结果:病原菌中75·0%来自分泌物标本。分离数居前四位的细菌是金黄色葡萄球菌、铜绿假单胞菌、鲍曼不动杆菌以及阴沟肠杆菌,分别占34·5%、17·0%、12·0%、6·0%。金葡菌中62·3%为耐甲氧西林株,仅对万古霉素和甲氧苄啶/磺胺甲唑的体外敏感性较好。铜绿假单胞菌、鲍曼不动杆菌和阴沟肠杆菌对三代头孢菌素耐药率相对较高,对哌拉西林/三唑巴坦、亚胺培南耐药率较低。结论:烧伤感染以金葡菌和铜绿假单胞菌为主,具有高度耐药性和多重耐药的特点。

Survilliance and Susceptibility Analysis of Pathogens isolated from Burn Unit during 2002 and 2005

Objective:To investigate the distribution and antibacterial susceptibility of pathogens in Burn Unit of West China hospital,and provide evidence for clinical therapy.Methods:A retrospective surveillance was carried out from 2002 to 2005.Identification and susceptibility of pathogens were assayed by Microscan Walkaway 40 Automatic System.Results:Seventy-five percent of bacteria were isolated from secretion specimens.The common four pathogens were Staphylococcus aureus,Pseudomonas aeruginosa,Acinetobacter baumanii,and Enterobacter cloacae,account for 34.5%,17.0%,12.0% and 6.0%,respectively.S.aureus were mostly Methecillin-resitant strains,and sensitive to Vancomycin and Trimethoprim-Sulfamethoxazole.And P.aeruginosa,A.baumanii,and E.cloacae were resistant to third-generation cephalosporin,which show relatively susceptible to Piperacillin/Tazobactam and Imipenem.Conclusion:Bacteria isorated from in Burn Unit were mainly S.aureus and P.aeruginosa with high-level resistance and multi-drug resistance.