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Quality of life differences in patients with typical atrial flutter following cavotricuspid isthmus ablation
Authors:García Seara Javier  Gude Francisco  Cabanas Pilar  Martínez Sande José Luis  Fernández López Xesús  Elices Juliana  Brugada Terradellas Josep  González Juanatey José Ramón
Affiliation:a Unidad de Arritmias, Servicio de Cardiología, Hospital Clínico Universitario, Santiago de Compostela, A Coruña, España
b Unidad de Epidemiología Clínica, Hospital Clínico Universitario, Santiago de Compostela, A Coruña, España
c Instituto de Investigaciones Sanitarias de Santiago de Compostela (IDIS), Santiago de Compostela, A Coruña, España
d Sección de Arritmias, Instituto del Tórax, Hospital Clínic de Barcelona, Barcelona, España
Abstract:

Introduction and objectives

The aim of the study was to assess and measure health-related quality of life (HRQoL) changes in patients with typical atrial flutter following catheter ablation. The outcome was standardized and normalized to the Spanish population adjusted by age and sex.

Methods

Ninety-five consecutive patients who had undergone cavotricuspid isthmus ablation were included. The SF-36 questionnaire was self-administered before the procedure and at 1-year follow-up. We used the effect size and the standardized response mean as measures of responsiveness to quantify the change in HRQoL and the minimum clinically important difference to assess the smallest difference in score that patients perceived as beneficial.

Results

Of the 95 patients initially included, 88 completed the 1-year follow-up. We observed a large improvement (effect size ≥0.8) on the physical functioning, role-physical , general health, and vitality scales and on the physical component summary. We detected a moderate improvement (effect size ≥0.5) on the role-emotional, social functioning, and mental health scales and on the mental component summary. On all scales except bodily pain and social activity, the improvement was clinically perceived by patients.

Conclusions

A clinically significant improvement in HRQoL measures was found in patients with typical atrial flutter who underwent cavotricuspid isthmus catheter ablation.Full English text available from: www.revespcardiol.org
Keywords:CVRS, calidad de vida relacionada con la salud   FlA, flutter auricular   ICT, istmo cavotricuspí  deo   MCID, diferencias clí  nicas mí  nimamente importantes   SRM, media de respuesta estandarizada   TE, tamañ  o de efecto
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