Changing epidemiology of native valve infective endocarditis |
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Authors: | Castillo Juan C Anguita Manuel P Ruiz Martín Peña Luisa Santisteban Marta Puentes Miguel Arizón José M Suárez de Lezo José |
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Institution: | Servicio de Cardiología, Hospital Universitario Reina Sofía, Córdoba, España |
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Abstract: | Introduction and objectivesThe aim of our study is to assess changes in the epidemiologic features of patients with native valve infective endocarditis.MethodsWe analyzed a prospective series of 228 cases of native valve infective endocarditis in non-intravenous drug users attending our center between 1987 and 2009. We compared three subperiods: 1987-1994 (67 cases), 1995-2002 (74 cases) and 2003-2009 (87 cases).ResultsThe mean age of patients has progressively increased (38±22 years in the first subperiod vs 60±16 years in the third; P<.001), as has the proportion of cases without predisposing heart disease (25%, 46% and 67%; P<.001). Incidence of mitral valve prolapse remained stable (12%, 18% and 11%). Percentages of patients with predisposing heart disease and who were aware of their condition have fallen in recent years (45%, 27% and 21%; P<.001). A portal of entry for the infection could not be identified in 64%. Overall, Staphylococcus aureus is the most frequent causative organism (26%) whereas the percentage of cases caused by Streptococcus viridans remains unaltered (22%, 20% and 24%).ConclusionsWe found significant changes in the epidemiology of native valve infective endocarditis. The incidence of patients without predisposing heart disease has increased significantly and staphylococci are the most frequent causative organisms.Full English text available from: www.revespcardiol.org |
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Keywords: | EI endocarditis infecciosa UDVP usuarios de drogas por ví a parenteral |
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