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Trisomy 18 in a canine thyroid adenoma |
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| Authors: | Nicola Reimann,Ingo Nolte,Ulrich Bonk,Martin Werner,Jö rn Bullerdiek,Sabine Bartnitzke |
| Affiliation: | a Center for Human Genetics and Genetic Counselling, University of Bremen, Bremen, Germany b Clinic for Small Animals, Hannover, School of Veterinary Medicine, Germany c Institute of Pathology, Central Hospital Bremen-Nord, Bremen, Germany d Institute for Pathology, Medical School, Hannover, Germany |
| Abstract: | A canine thyroid adenoma showing trisomy 18 as the sole clonal cytogenetic abnormality (9 of 30 analyzed metaphases) is reported. Because trisomies are a recurrent cytogenetic finding in human benign thyroid tumors as well, it is suggested that the molecular relationship between these trisomies and the development of thyroid tumors can be determined by comparative gene mapping. |
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