Characterization of adjacent breast tumors using oligonucleotide microarrays期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Characterization of adjacent breast tumors using oligonucleotide microarrays

Authors:	Unger M A Rishi M Clemmer V B Hartman J L Keiper E A Greshock J D Chodosh L A Liebman M N Weber B L

Affiliation:	(1) University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA;(2) Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA;(3) Department of Pathology, St Francis Hospital, Wilmington, Delaware, USA;(4) Department of Surgery, St Francis Hospital, Wilmington, Delaware, USA;(5) Department of Molecular and Cellular Engineering, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA;(6) Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA;

Abstract:	Background Current methodology often cannot distinguish second primary breast cancers from multifocal disease, a potentially important distinction for clinical management. In the present study we evaluated the use of oligonucleotide-based microarray analysis in determining the clonality of tumors by comparing gene expression profiles.

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