| pN0声门上型喉癌微血管密度和颈淋巴结微转移灶的研究 |
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| 引用本文： | 李丙华,徐娅苹,苏立众,陈明媛. pN0声门上型喉癌微血管密度和颈淋巴结微转移灶的研究[J]. 临床耳鼻咽喉头颈外科杂志, 2009, 23(18): 824-826 |
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| 作者姓名： | 李丙华 徐娅苹 苏立众 陈明媛 |
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| 作者单位： | 1. 浙江省人民医院耳鼻咽喉科,杭州,310014
2. 浙江大学医学院附属第二医院耳鼻咽喉科 |
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| 摘 要： | 目的：探讨pN0声门上型喉癌瘤内微血管密度（IMVD）与颈淋巴结微转移的相关性及其临床意义。方法：分别应用CD105和CK19单克隆抗体进行免疫组织化学SABC法检测pN0声门上型喉癌IMVD及颈淋巴结微转移灶。结果：CD105标记的IMVD与喉癌的T分期和颈淋巴结微转移密切相关（P〈0．01）。结论：pN0喉癌IMVD与颈淋巴结微转移高度相关，二者可作为pN0喉癌患者独立的预后指标。
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| 关 键 词： | 喉肿瘤 微血管密度 微转移 |
A study of intratumor microvessel density and lymph node micrometastasesof pN0 supraglottic laryngeal squamous cell carcinoma |
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| LI Binghua,XU Yaping,SU Lizhong,CHEN Mingyuan. A study of intratumor microvessel density and lymph node micrometastasesof pN0 supraglottic laryngeal squamous cell carcinoma[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2009, 23(18): 824-826 |
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| Authors: | LI Binghua XU Yaping SU Lizhong CHEN Mingyuan |
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| Affiliation: | 1Department of Otolaryngology;Zhejiang Provincial People's Hospital;Hangzhou;310014;China;2Department of Otolaryngology;the Second Affiliated Hospital;Medical College of Zhejiang University |
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| Abstract: | Objective:To investigate the correlation between intratumor microvessel density(IMVD)and lymph node micrometastases.Method:IMVD and lymph node micrometastases were stained with CD105 and CK19 antibody by immunohistochemical method of SABC respectively.Result:IMVD marked with CD105 antibody correlated with T stage and lymph node micrometastases(P<0.01).Conclusion:The result show that IMVD marked with CD105 antibody highly correlated with lymph node micrometastases.It could be a index to evaluate the prognosi... |
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| Keywords: | laryngeal neoplasms microvessel density micrometastases |
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