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Clinical Utility of Videofluorography with Concomitant Tensilon Administration in the Diagnosis of Bulbar Myasthenia Gravis
Authors:Darren?C?Schwartz  Andrew?J?Waclawik  Sumit?N?Ringwala  Email author" target="_blank">Joanne?RobbinsEmail author
Institution:(1) Departments of Medicine, Section of Gastroenterology & Hepatology, University of Wisconsin Medical School, USA;(2) Department of Neurology, University of Wisconsin Medical School, USA;(3) William S. Middleton Veterans Affairs Hospital, Madison, Wisconsin, USA;(4) Geriatric Research Education & Clinical Center, Madison, Wisconsin, USA;(5) University of Wisconsin Medical School, 600 Highland Avenue H6/516, Madison, Wisconsin 53792, USA
Abstract:Myasthenia gravis (MG) classically presents with ocular, bulbar, and predominantly proximal muscle weakness. Isolated bulbar symptoms occur in less than 25% of cases and can mimic stroke (1–3). If left untreated, MG can lead to significant morbidity and mortality, including myasthenic crisis and recurrent aspiration pneumonia. We describe a case of a 68-year-old man who presented with isolated bulbar symptoms. We used a novel approach to diagnosis which included a videofluorographic swallow study with concomitant Tensilon (edrophonium) injection.
Keywords:myasthenia gravis  videofluorography  bulbar  Tensilon  dysphagia
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