Depression and partial epilepsy: Relevance of laterality of the epileptic focus |
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| Authors: | L. Septien M. Giroud R. Didi-Roy J.L. Pelletier A. Marin R. Dumas |
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| Affiliation: | 1. Department of Mental Health, U.N.A.M. Mexico, C.H.U. Dijon;2. Service de Neurologie C.H.U. Dijon, C.H.U. Dijon;3. Service de Psychiatrie de la Chartreuse, Dijon, C.H.U. Dijon;4. Centre de Medecine Nucleaire du Parc Dijon C.H.U. Dijon;5. Service de Psychiatrie, C.H.U. Dijon |
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| Abstract: | AbstractIn a prospective study of 50 epileptic patients (20 with a left hemisphere epileptic focus, 20 with a right one and 10 with a cryptogenic generalized epilepsy), the authors show that depression as appreciated by the H.A.R.D. score, is more frequent and severe in partial epilepsy in males, and when the epileptic focus is localized on left hemisphere. This association is related to the duration of epilepsythe number of seizures, but not to age or medication status.. Vulnerability of left hemisphere to depression is analysedand neuro-chemical mechanisms are discussed. [Neurol Res 1993; 15: 136-138] |
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| Keywords: | Partial epilepsy depression left hemisphere |
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