| 抑郁症患者局部脑血流的研究 |
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| 引用本文： | 兰光华,赵海园,徐峰波.抑郁症患者局部脑血流的研究[J].临床精神医学杂志,2004,14(1):12-13. |
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| 作者姓名： | 兰光华 赵海园 徐峰波 |
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| 作者单位： | 1. 215006,苏州大学附属第一医院精神科
2. 215006,苏州大学附属第一医院核医学科 |
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| 基金项目： | 苏州大学附属第一医院科技基金课题 (H983 6) |
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| 摘 要： | 目的：了解抑郁症患者局部脑血流灌注的特点：方法：应用单光子发射计算机断层扫描对20例抑郁症患者及18例正常对照者局部脑血流灌注进行对比分析。结果：抑郁症组双侧基底核、双侧额叶、左颞叶及左枕叶局部血流低灌注；抑郁症组与对照组左右大脑半球局部血流灌注无显著性差异：结论：抑郁症患者局部脑血流存在低灌注，但未发现局部脑血流低灌注有侧化现象。
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| 关 键 词： | 抑郁症 局部脑血流 单光子发射计算机断层扫描 |
| 文章编号： | 1005-3220(2004)01-0012-02 |
| 修稿时间： | 2003年6月13日 |
Study of regional cerebral blood flow in major depression |
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| LAN Guang-hua,ZHAO Hai-yuan,XU Feng-po.Study of regional cerebral blood flow in major depression[J].Journal of Clinical Psychological Medicine,2004,14(1):12-13. |
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| Authors: | LAN Guang-hua ZHAO Hai-yuan XU Feng-po |
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| Institution: | LAN Guang-hua,ZHAO Hai-yuan,XU Feng-po.The Department of Psychiatry,the First Affiliated Hospital of Suzhou University,Suzhou 215006 |
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| Abstract: | Objective:To understand the characteristic of regional cerebral blood flow (rCBF) in major depression. Method:Twenty patients with major depressive disorder were studied at rest using SPECT in comparison with 18 normal controls. Results: The depressed group showed lower rCBF in bilateral basal ganglia and frontal lobes,left temporal lobe and occipital lobe than normal controls.Lateralization of hypoperfusion was not supported by our study. Conclusion:There was a lower perfusion of regional cerebral flow,but there was not a lateralization of hypoperfusion in major depression. |
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| Keywords: | Major depression Regional cerebral blood flow Single photon emission computedtomograpy |
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