Decomposition-based quantitative electromyography: methods and initial normative data in five muscles

Quantitative electromyographic (EMG) techniques provide clinically useful information to aid in the diagnosis and follow the course or response to treatment of diseases affecting the motor system. The purpose of this study was to describe a decomposition-based quantitative electromyography method (DQEMG) designed to obtain clinically applicable information relating to motor unit potential (MUP) size and configuration, and motor unit (MU) firing characteristics. Additionally, preliminary normative data were obtained from the deltoid, biceps brachii, first dorsal interosseous, vastus medialis, and tibialis anterior muscles of 13 control subjects. DQEMG was capable of efficiently and accurately extracting MUP data from complex interference patterns during mild to moderate contractions. MUP amplitude, surface-detected MUP (S-MUP) amplitude, MUP duration, number of phases, and MU firing frequencies varied significantly across muscles. The mean parameter values for the individual muscles studied were similar to previous reports based on other quantitative methods. The main advantages of this method are the speed of data acquisition and processing, the ability to obtain MUPs from MUs with low and higher recruitment thresholds, and the ability to obtain both S-MUP or macro-MUP data as well as MU firing rate information.