| SCAP和SHAP患者病原体和高危因素研究 |
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| 引用本文： | 杨松,张耀亭.SCAP和SHAP患者病原体和高危因素研究[J].中国病原生物学杂志,2011(3). |
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| 作者姓名： | 杨松 张耀亭 |
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| 作者单位： | 解放军第175医院;厦门大学附属东南医院呼吸科; |
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| 摘 要： | 目的探讨重症社区获得性肺炎(SCAP)和重症医院获得性肺炎(SHAP)患者分离的病原体及高危因素。方法收集SCAP和SHAP住院患者的临床资料,分离痰、血清或骨髓等标本病原体;对比分析SCAP和SHAP病原体和高危因素。结果 25例SCAP患者病原体阳性12例,明确病原菌16株,其中革兰阳性球菌5株,真菌6株,革兰阴性杆菌3株和肺炎支原体2株。98例SHAP患者病原体阳性95例,分离病原菌131株。20例早发SHAP患者分离病原菌22株,其中革兰阳性球菌14株,革兰阴性杆菌7株,白色念珠菌1株;78例晚发SHAP患者明确病原菌109株,其中革兰阴性杆菌81株,革兰阳性球菌18株,真菌10株。仅28.00%(7例)SCAP具有危险因素;SHAP的常见高危因素有气管切开或插管、机械通气和高龄。结论 SCAP患者病原体分离率显著低于SHAP,SCAP最常见病原体为真菌和革兰阳性球菌,早发SHAP病原体大多为葡萄球菌,晚发SHAP主要为革兰阴性杆菌中的肺炎克雷伯菌、鲍曼/溶血不动杆菌和铜绿假单胞菌,其次为革兰阳性球菌和真菌。SCAP高危因素少,而SHAP具有多种高危因素。
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| 关 键 词： | 重症肺炎 社区获得性肺炎 医院获得性肺炎 病原体 高危因素 |
Study on the risk factors for and pathogens causing severe community-acquired pneumonia and severe hospital-acquired pneumonia in patients |
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| YANG Song,ZHANG Yao-ting.Study on the risk factors for and pathogens causing severe community-acquired pneumonia and severe hospital-acquired pneumonia in patients[J].Journal of Pathogen Biology,2011(3). |
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| Authors: | YANG Song ZHANG Yao-ting |
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| Institution: | YANG Song,ZHANG Yao-ting(Department of Respiratory Diseases,175th Hospital,PLA/Dongnan Hospital Affiliated with Xiamen University,Zhangzhou,363000,Fujian,China) |
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| Abstract: | Objective To explore the risk factors for and pathogens causing severe community-acquired pneumonia and severe hospital-acquired pneumonia in patients.Methods Clinical data on SCAP and SHAP were collected.Pathogens were isolated from sputum,sera,or bone marrow.Etiology and high-risk factors were then analyzed comparatively.Results Pathogens were isolated from 12 of 25 patients with SCAP.Sixteen etiological bacteria strains were found,including 5 strains of Gram-positive cocci,6 of fungi,2 of Gram-negative b... |
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| Keywords: | Severe pneumonia community-acquired pneumonia hospital-acquired pneumonia pathogen high-risk factors |
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