| WU多瘤病毒在儿童急性呼吸道感染中的作用 |
| |
| 引用本文： | 李晓燕,陈锦英,孔梅,苏旭,易艳萍,邹明,张桦,韩玉敏.WU多瘤病毒在儿童急性呼吸道感染中的作用[J].中国病原生物学杂志,2011(1). |
| |
| 作者姓名： | 李晓燕 陈锦英 孔梅 苏旭 易艳萍 邹明 张桦 韩玉敏 |
| |
| 作者单位： | 天津市疾病预防控制中心;天津医科大学基础医学院;天津儿童医院;天津市咸水沽医院; |
| |
| 基金项目： | 天津市科技支撑重大项目(No.07SYSYSF05100) |
| |
| 摘 要： | 目的了解急性呼吸道感染儿童中WU多瘤病毒(WUPyV)的感染情况及其作用。方法采集天津市儿童医院急性下呼吸道感染住院儿童的鼻咽吸取物(NPA)标本174份,急性上呼吸道感染的咽拭子标本68份以及无呼吸道症状的对照咽拭子标本43份,用PCR法进行WUPyV基因检测,对NPA阳性标本采用PCR和多重PCR同时检测其他常见呼吸道病毒。结果174份NPA标本中共28份检出WUPyV核酸,占16.1%。患者平均年龄为11.7个月(12 d~39个月),其中≤6个月10例(35.7%),6个月~1岁10例(35.7%),1~2岁7例(25.0%),2~5岁1例(3.6%);男19例(67.9%),女9例(32.1%);与其他呼吸道病毒混合感染20例,占71.4%,50%为两种病毒混合感染,混合感染率最高的为RSVB(32.1%),其次为HboV(21.4%)和Rhino、PIV3(均为14.3%)。检查68例急性上呼吸道感染者的咽拭子标本,3例为WUPyV阳性,其中2例患儿为3岁,1例2岁;女2例,男1例。43例无呼吸道症状者的咽拭子标本均为WUPyV阴性。结论急性呼吸道感染儿童中存在WUPyV感染,下呼吸道感染患儿中检...
|
| 关 键 词： | WUP多瘤病毒 急性呼吸道感染 流行病学 儿童 |
Role of WU polyomavirus in children with acute respiratory tract infections |
| |
| LI Xiao-yan,CHEN Jin-ying,KONG Mei,SU Xu,YI Yan-ping,ZOU Ming,ZHANG Hua,HAN Yu-min.Role of WU polyomavirus in children with acute respiratory tract infections[J].Journal of Pathogen Biology,2011(1). |
| |
| Authors: | LI Xiao-yan CHEN Jin-ying KONG Mei SU Xu YI Yan-ping ZOU Ming ZHANG Hua HAN Yu-min |
| |
| Abstract: | Objective To investigate the potential role of WU polyomavirus in respiratory disease,the frequency of its detection and its epidemiological characteristics were determined in children with and without respiratory infections.Methods Nasopharyngeal aspirates(NPA) were collected from 174 hospitalized pediatric patients from Mar.to Apr.in 2008 and from Sep.2008 to Feb.2009.VP2 gene fragments of WUPyV were first examined by PCR amplification and then verified by PCR amplification of LTAg gene fragments.All WUPy... |
| |
| Keywords: | WU polyomavirus acute respiratory tract infections epidemiology child |
| 本文献已被 CNKI 等数据库收录！ |
|
