| 金胆片浸膏的主要药效学研究 |
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| 引用本文： | 仇士东,赵爱丽,焦健.金胆片浸膏的主要药效学研究[J].齐鲁药事,2007,26(10):623-625. |
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| 作者姓名： | 仇士东 赵爱丽 焦健 |
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| 作者单位： | 1. 山东省医药工业研究所,山东,济南,250100
2. 山东大学齐鲁医院,山东,济南,250100 |
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| 摘 要： | 目的观察金胆片浸膏对小鼠的镇痛、抗炎作用以及对大鼠的利胆作用。方法采用二甲苯致炎剂,观察金胆片浸膏对由此而产生耳廓肿胀作用的影响;观察金胆片浸膏对醋酸刺激所致疼痛的影响;观察金胆片浸膏对大鼠胆汁流量的影响。结果金胆片浸膏对二甲苯所致的小鼠耳肿胀有明显的抑制作用,对醋酸所致小鼠扭体反应也有明显抑制作用,能明显增加大鼠胆汁流量。结论金胆片浸膏具有镇痛、抗炎、利胆作用。
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| 关 键 词： | 金胆片 抗炎 镇痛 利胆 |
| 文章编号： | 1672-7738（2007）10-0623-03 |
Pharmacodynamic Study of Jindan Pian extract |
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| QIU Shi-dong,ZHAO Ai-li,JIAO Jian.Pharmacodynamic Study of Jindan Pian extract[J].qilu pharmaceutical affairs,2007,26(10):623-625. |
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| Authors: | QIU Shi-dong ZHAO Ai-li JIAO Jian |
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| Abstract: | OBJECTIVE To observe the analgesic,anti-inflammatory and cholagogic effect of Jindan Pian extract to mice.METHODS By using model of turning of trunk,the pain releasing effect of Jindan Pian extract was evaluated.The experiments about anti-inflammation and cholagogic action of Jindan Pian extract.RESULTS Animal experiment showed that this kind of extract had obvious inhibitory actions on swelling of auricular concha of mice induced by dimethylbenzene.It also had a remarkable inhibition on both torsion response of mice induced by acetic acid.It can increase bile current capacity.CONCLUSION Jindan Pian extract could release the pain,suppress the inflammation and increase bile current capacity. |
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| Keywords: | Jindan Pian anti-inflammation analgesic action cholagogic |
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