支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿的效果观察

目的 观察支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿的效果.方法 选择灵山县人民医院2011年1月～2014年1月收治的急性肺脓肿患者120例,按随机数字表法分为大剂量氨溴索灌洗60例（治疗组）和生理盐水灌洗60例（对照组）,两组均每周灌洗2次,疗程2～4周,于治疗后4周复查胸部CT.结果 治疗组治愈率为95％,明显高于对照组治愈率40％,治疗组灌洗次数（4.3±1.3）次]较对照组灌洗次数（5.4±1.4）次]明显减少,治疗组抗菌药疗程（16.2±2.7）d]较对照组抗菌药疗程（24.8±3.1）d]明显缩短,治疗组住院时间（17.8±4.3）d]较对照组住院时间（25.3±3.5）d]明显缩短,差异有高度统计学意义（P＜0.01）.结论 支气管肺泡灌洗大剂量氨溴索治疗急性肺脓肿是一种很好的治疗手段.

Observation of effect of high dose ambroxol lavage through bronchoalveolar treating acute pulmonary abscess

Objective To observe the therapeutic effect of high dose ambroxol lavage through bronchoalveolar treating acute pulmonary abscess.Methods 120 patients with acute pulmonary abscess admitted to People＇s Hospital of Lingshan City from January 2011 to January 2014 were chosen and divided into two groups by random number method.The treatment group （60 cases） was given high dose ambroxol lavage,and the control group （60 cases） was given normal saline lavage,both groups were given lavage 2 times per week,for 2-4 weeks; and both groups were chest CT examination after the treatment for 4 weeks.Results The cure rate of treatment group was 95％,higher than that of control group （40％）,the differences were statistically significant （P ＜ 0.01）,the lavage frequency of treatment group （4.3±1.3）times] were significantly decreased than that of control group （5.4±1.4） times],the differences were statistically significant （P ＜ 0.01）,the antimicrobial treatment time of treatment group （16.2±2.7） days] were obviously shorter than that of control group （24.8±3.1） days],the differences were statistically significant （P ＜ 0.01）,the hospital stay times of treatment group （17.8±4.3） days] were obviously shortened than that of control group （25.3±3.5） days] the differences were statistically significant （P ＜ 0.01）.Conclusion High dose ambroxol lavage through bronchoalveolar is a good treatment method for acute pulmonary abscess.