社区人群脂肪肝患病率及其相关因素的流行病学调查

目的探讨广州市荔湾区社区居民脂肪肝的患病率及相关危险因素。方法按照随机抽样的方法,选取广州市荔湾区社区居民共800人为调查对象,采用问卷调查、体格检查、血脂检查及肝脏B超检查,比较不同人群脂肪肝患病情况及相关因素。结果总人群脂肪肝患病率为21.0%。男性脂肪肝患病率(26.75%)显著高于女性(15.06%)(P<0.01)。脂肪肝组总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、收缩压(SBP)、舒张压(DBP)均高于非脂肪肝组(P<0.01)。Logistic回归分析结果显示,性别(男性)、血压、腰臀比(WHR)、体重指数(BMI)、TC、糖尿病(DM)、腰围(WC)为脂肪肝的危险因素(P<0.05)。结论广州市荔湾区脂肪肝患病率较高,男性、血压、WHR、BMI、TC、DM、WC是导致脂肪肝的主要危险因素。

Prevalence and risk factors of fatty liver disease in community population

Objective To discuss the prevalence and risk factors of fatty liver disease in Liwan District of Guangzhou City. Methods 800 community residents of Liwan District of Guangzhou City were investigated by random sampling method. The survey included questionnaire investigation, medical check-up, blood-fat examination and ultrasonography. Fatty liver disease prevalence of different crowd were compared, the related factors were analyzed. Results The total incidence of fatty liver disease was 21.0%. The incidence of fatty liver disease in male（26.75%） was higher than that in female（15.06%）（P 0.01）. The TC, TG, HDL-C, LDL-C, SP and DP were higher in fatty liver disease group than in the non- fatty liver disease group（P 0.01）. Logistic regression analysis revealed that risk factors of fatty liver disease included male, blood pressure, WHR, BMI, TC, DM and WC（P 0.05）. Conclusion A high prevalence of fatty liver disease is found in Liwan District of Guangzhou City, the risk factors of fatty liver disease are associated with male, blood pressure, WHR, BMI, TC, DM and WC.