肿瘤患者中心静脉导管置管感染的药学监护

目的探讨肿瘤患者中心静脉导管（nEE）置管感染的药学监护。方法临床药师运用临床药学理论知识，结合血管内导管相关感染的预防与治疗指南原则，对1例晚期胆管癌合并糖尿病的PICC置管感染患者进行全程药学监护，制订个体化给药方案。结果对于PICC置管感染的肿瘤患者，临床药师根据病原菌分布特点、药敏实验结果及患者的具体病生理变化情况进行药学监护，使抗感染从经验治疗、目标治疗、治疗方案制订，停药时间以及规避严重不良反应方面全程药学监护，使感染得到控制，患者临床用药安全、有效。结论临床药师参与PICC置管感染肿瘤患者的临床治疗，全程实施药学监护，制订个体化给药方案，保障了患者用药的安全性和有效性．提高了肿瘤患者PICC置管感染的治愈率，也初步总结出肿瘤患者PICC置管感染的药学监护模式。

Pharmaceutical care of cancer patients with PICC catheter infection

Objective To discuss the tumor patients with peripherally inserted central catheter （PICC） catheter infection of pharmaceutical guardianship content. Methods Theory of clinical pharmacy knowledge and in combination with in- travascular catheter related infections of the principle of prevention and treatment guidelines were applied by clinical pharmacists, 1 case with bile duct carcinoma combined with diabetes mellitus and PICC catheter infection was given the entire pharmaceutical care, and individualized dosage regimen was formulated. Results For tumor patients with PICC catheter infection, clinical pharmacists according to the result of pathogenic bacteria distribution and drug sus- ceptibility experiment and physiological changes in specific disease of patients with pharmaceutical care, made the an- ti-infection treatment from the experience, target therapy, treatment plan formulation, time of drug discontinuance and avoid serious adverse reactions in the entire pharmaceutical care, to control infection, patients with safe and effective clinical application. Conclusion Cancer patients with PICC catheter infection with the help of clinical pharmacists in clinical treatment, the full implementation of pharmaceutical care, setting individualized dosage regimen, and ensure the patient safety and effectiveness, improve the cure rate of cancer patients with PICC catheter infections ,also prelim- inarily conclude pharmaceutical care mode of cancer patients with PICC catheter infection.