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Association of varicella zoster dermatitis with acute retinal necrosis syndrome
Authors:D J Browning  M S Blumenkranz  W W Culbertson  J D Clarkson  Y Tardif  A Gourdeau  J Minturn
Affiliation:1. Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America;2. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, United States of America;3. Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America;4. Department of Ophthalmology, The Permanente Medical Group, Vallejo, CA, United States of America;5. Division of Ophthalmology, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America;6. Department of Neurology, Brigham and Women''s Hospital, Harvard Medical School, Boston, MA, United States of America;7. Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America
Abstract:The authors report seven patients in whom the acute retinal necrosis (ARN) syndrome developed shortly after cutaneous varicella zoster infection. The length of time between the skin infection and ARN varied from 5 days to 3 months. Both eyes were affected in one of seven cases. The ophthalmic branch of cranial nerve V ipsilateral to an affected eye was involved by the zoster dermatitis in only two of the seven cases. The association lends further support to the proposal that herpes zoster virus is a major cause of ARN. A history of recent zoster dermatitis should be sought in patients with ARN.
Keywords:acute retinal necrosis syndrome  herpes zoster  varicella zoster
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