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| PPE复方制剂对大鼠烧伤治疗的实验研究 | |
| 引用本文： | 傅映平,孙千鸿,刘彦,陈媛,舒晔,杨建宇. PPE复方制剂对大鼠烧伤治疗的实验研究[J]. 昆明医学院学报, 2010, 31(6): 11-15 |
| 作者姓名： | 傅映平 孙千鸿 刘彦 陈媛 舒晔 杨建宇 |
| 作者单位： | 1. 昆明医学院海源学院药理教研室,云南昆明,650031 2. 昆明医学院海源学院化学教研室,云南昆明,650031 3. 昆明医学院海源学院病理教研室,云南昆明,650031 4. 昆明医学院海源学院医学机能学实验室,云南昆明,650106 5. 昆明医学院药理教研室,云南昆明,650031 |
| 基金项目： | 云南省教育厅科研基金资助项目 |
| 摘 要： | 目的观察PPE软膏局部用药对大鼠颈背部皮肤Ⅱ～Ⅲ度烧伤的治疗作用.方法用PPE软膏涂搽皮肤烧伤创口部位,并以美宝湿润烧伤膏作阳性对照组,设空白对照组（不给予任何药物治疗）.1次/2d,连续30d.各组大鼠每天均观察其脱痂和长毛时间以及食量和活动度.分别于11d和31d两次做病理组织切片进行病理检查.结果 PPE组和美宝组软膏局部涂搽后,分别与空白对照组比较,其对大鼠颈背部皮肤Ⅱ～Ⅲ度烧伤的脱痂时间（P〈0.05）和长毛时间（P〈0.05）均缩短并具有统计学意义;PPE组对大鼠烧伤坏死创面有修复作用.结论 PPE对大鼠颈背部皮肤Ⅱ～Ⅲ度烧伤有明显的治疗作用. |
| 关 键 词： | PPE复方制剂 烧伤治疗 实验研究 |
An Experimental Research on the Treatment of Burn Rats with PPE Compound Preparation |
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| FU Ying-ping,SUN Qian-hong,LIU Yan,CHEN Yuan,SHU Ye,YANG Jian-yu. An Experimental Research on the Treatment of Burn Rats with PPE Compound Preparation[J]. Journal of Kunming Medical College, 2010, 31(6): 11-15 | |
| Authors: | FU Ying-ping SUN Qian-hong LIU Yan CHEN Yuan SHU Ye YANG Jian-yu |
| Affiliation: | 1) Dept. of Pharmacology;2) Dept. of Chemistry;3) Dept. of Pathology;4) Functional Laboratory,Haiyuan College,Kunming Medical University,Kunming Yunnan 650106;5) Dept. of Pharmacology,Kunming Medical University,Kunming Yunnan 650031,China) |
| Abstract: | Objective To observe the effectiveness of PPE local medicine on the treatment of the neck and back skin burn of rats （Ⅱ～Ⅲ）.Methods PPE salves with different concentration were smeared on the burn locus of the rats once every two days for thirty days.Mei Bao Moisturing salves was taken as a positive control group and a no medicine group was also observed.The time of decrustation and fur-growing,appetite and activity of the rats in each group,were observed everyday.The histopathologal changes were observed on 11 d and 31 d after treatment.Results Compared with no medicine group,the time of the decrustation （P0.05） and the fur-growing （P0.05） of the neck and back skin burn of rats （Ⅱ～Ⅱ）I was shortened in PPE and Mei Bao Moisturing Salve group,and the difference showed a significance.PPE had a repair effect on the neck and back skin burn of rats.Conclusion PPE compound preparation has a noticeable effect in the treatment of the neck and back skin burn of rats （Ⅱ～Ⅲ）. |
| Keywords: | PPE compound preparation Burn treatment Experimental research |
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