| 螺旋藻多糖对人宫颈癌Hela细胞体外生长的影响 |
| |
| 引用本文： | 丁守怡,杨英. 螺旋藻多糖对人宫颈癌Hela细胞体外生长的影响[J]. 青岛大学医学院学报, 2002, 38(4): 340-347 |
| |
| 作者姓名： | 丁守怡 杨英 |
| |
| 作者单位： | 1. 青岛大学医学院微生物学教研室,青岛,266021
2. 青岛大学医学院附属医院药剂科,青岛,266021 |
| |
| 摘 要： | 目的：探讨螺旋藻多糖（PSP）对体外培养的Hela细胞生长的影响。方法：采用MTT法测定 PSP的抗肿瘤活性，并观察其对Hela细胞形态学的影响。结果：随PSP浓度的升高，Hela细胞存活率逐渐降低，抑制率逐渐增加；光镜下观察显示，PSP作用24-48h后，细胞出现明显的形态学改变。结论：PSP能抑制Hela细胞增殖。
|
| 关 键 词： | 螺旋藻多糖 宫颈肿瘤 Hela细胞 细胞分裂 MTT比色法 |
| 文章编号： | 1001-4047(2002)04-0346-02 |
| 修稿时间： | 2002-06-04 |
EFFECTS OF POLYSACCHARIDES FROM SPIRULINA PLATENSIS ON THE GROWTH OF Hela CELLS: AN IN VITRO STUDY |
| |
| DING Shouyi,YANG Ying . EFFECTS OF POLYSACCHARIDES FROM SPIRULINA PLATENSIS ON THE GROWTH OF Hela CELLS: AN IN VITRO STUDY[J]. Acta Academiae Medicinae Qingdao Universitatis, 2002, 38(4): 340-347 |
| |
| Authors: | DING Shouyi YANG Ying |
| |
| Affiliation: | DING Shouyi,YANG Ying Department of Microbiology,Qingdao University Medical College,Qingdao 266021 |
| |
| Abstract: | Objective To study the effects of polysaccharide from Spirulina platensis (PSP) on the growth of Hela cells in vitro. Methods MTT assay was applied to evaluate the antitumor activity of PSP on Hela cells and its influence on the cell morphological changes was observed. Results With the increase of PSP concentration , the inhibition rate on Hela cells increased and the survival rate declined. Evident morphological changes of Hela cells, exposed to PSP for 24-48 hours, were seen microscopically. Conclusion PSP can inhibit the proliferation of Hela cells. |
| |
| Keywords: | polysaccharides from Spirulina platensis cervix neoplasms Hela cells cell division MTT chromatometry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
