外科重症监护室医院感染病原菌分析 FREE

目的通过对外科重症监护室（SICU）医院感染（NI）病原菌的特点分析,指导SICU医生经验选择抗菌药物治疗。方法对某院SICU 2006年发生NI患者的病历进行回顾性分析。结果SICU患者NI率为11.67%（70/600），其中单纯细菌感染42例（60.00%），单纯真菌感染2例（2.86%），混合感染（真菌+细菌）13例（18.57%）,微生物学培养阴性13例（18.57%）。常见细菌前5位依次为屎肠球菌（18.49%）、耐甲氧西林金黄色葡萄球菌（17.65%）、耐甲氧西林凝固酶阴性葡萄球菌（17.65%）、铜绿假单胞菌（9.24%）、大肠埃希菌（7.56%）；G+球菌占52.90%。常见真菌前3位依次为曲霉菌（31.58%）、白假丝酵母菌（26.32%）和光滑假丝酵母菌（21.05%）；发生真菌感染者住SICU时间明显延长（P＜0.05），且住院病死率高达46.67%（7/15）。结论SICU患者NI率较高，以细菌感染为主，混合真菌感染次之。感染的细菌中，以G+球菌为主；真菌感染以曲霉菌、白假丝酵母菌和光滑假丝酵母菌为主。SICU发生真菌感染患者的住院时间明显延长，预后差。

Pathogens in nosocomial infection in surgical intensive care unit FREE

Objective To analyse the pathogens in nosocomial infection （NI） in surgical intensive care unit （SICU）, so as to guide clinicians to use antimicrobial agents properly. Methods Medical records of patients with NI in SICU at a hospital in 2006 were analysed retrospectively. Results NI rate in SICU patients was 11.67%（70/ 600）, 42 cases（60. 00%） were simple bacterial infection, 2 （2. 86%） were fungi infection, 13 （18. 57%） were mixed infection （bacteria and fungi）, 13 （18. 57%） were negative for microbial culture. The first five common bacteria in infection were Enterococcus faecium （18. 49 %）, methicillin-resistant staphylococcus aureus （ 17. 65 % ）, methicillin-resistant coagulase negative Staphylococcus （17. 65 % ）, Pseudornonas aeruginosa （9. 24%） and Escherichia coli （7. 56%）; gram-positive cocci was 52. 90%. The first three common fungi were Aspergillus spp. （31.58M）, Candida albicans （26. 32%） and Candida glabrata （21.05%）. The length of ICU stay was prolonged in patients with fungi infection （P〈0. 05）, and mortality in patients with fungi infection was 46. 67%（7/15）. Conclusion NI rate in patients in SICU is high, the most common infection are bacteria infection, mixed infection are the second. The most common bacteria is gram-positive cocci; The common fungi are Aspergillus spp. , Candida albicans and Candida glabrata, successively. The length of ICU stay is prolonged and the prognosis is poor in patients with fungi infection.