70例小儿葡萄球菌败血症药敏及抗菌药应用分析

目的:探讨某医院小儿葡萄球菌败血症的药物敏感试验及抗菌药物应用情况,规范抗菌药物的合理应用。方法:回顾性分析70例小儿葡萄球菌败血症药敏结果及抗菌药使用情况等临床资料。结果:致病菌以金黄色葡萄球菌为主。各菌种对药物敏感度依次为:万古霉素、米诺霉素和替考拉宁等;对青霉素耐药率100%。抗菌药使用频度由高到低为头孢硫脒、氨苄青霉素、夫西地酸钠等。结论:临床医生必须合理使用抗生素,尽量减少耐药菌的产生。在低年龄组葡萄球菌败血症中,建议将头孢硫脒和夫西地酸钠、替考拉宁可作为经验性治疗药使用。

The Applied Analysis of the Drug Sensitive Test of Pediatric Staphylococcal Septicemia and Antibacterial Drugs with 70 Cases of Children

Objective： To investigate our hospital＇s drug sensitive test of pediatric staphylococcal septicemia and antibacterial drugs application status , improve the reasonable application of antibacterial drugs.Method： Retrospectively analysed 70 cases of pediatric staphylococcal sepsis susceptibility results and antibacterial drug use and other clinical data. Results ： The pathogenic bacteria is dominated by staphylococcus aureus. The strains are highly sensitive to the drugs followed by vancmycin,teicoplanin_and minocycline The penicillin resistance rate of 100%. The using frequency of all kinds of antibacterial drug from high to low is Cephathiamidin, ampicillin, fusidic acid sodium. Conclusion： Clinicians should be reasonable use of antibiotics, minimizing the coming of sdrug-resistance bacteria. In the low age group Staphylococcus septicemia, suggesting that cefathiamidine and fusidic acid sodium, teicoplanin may be used as empiric therapy drugs.