60例中枢神经系统新型隐球菌感染脑脊液检测与临床分析

目的：分析中枢神经系统（ｃｅｎｔｒａｌ ｎｅｒｖｏｕｓ　ｓｙｓｔｅｍ，ＣＮＳ）新型隐球菌感染临床特征。方法：对 ６０例患者进行临床分析。结果：患者脑脊液呈无色浑浊、白细胞升高、其中以淋巴细胞和单核细胞为主。蛋白质升高、葡葡糖和氯化物减低，墨汁染色及苏木素－伊红染色均可发现新型隐球菌。几乎所有的患者有头痛、９０％有发热、７３％有呕吐、６５％有不同程度的意识障碍和偏瘫、约半数还有听力减退、双目失明和抽搐。结论：脑脊液墨汁或苏木素－伊红染色检查有助于鉴别。

A Cerebrospinal Fluid (CSF) Inspecting and Clinic Analysis of 60 Cases Patients Infected with Cryptococ-cus Neoformans in Central Nervous System (CNS)

Aim: To analyse the clinic manifestation of patients infected with cryptococcus neoformans in CNS. Methods: 60 cases had been analysed and counted. Results: The CSF changes showed: no colour and turbidness, white blood cells were raised,lymphocytes and mononuclears being prevailed ;protein increased ;glucose and chloride were declined. Cryptococcus neo- formans had been found with India-ink/hematoxylin-eosin staining. The clinic manifestations of patients were headache(nearly l 00 % ), fever (90 % ) .vomiting (73 % ) iconsciousness disorder and hemiplegia (65 % ) ; hearing declined,losing the sight of both eyes and twitch (50% ). Conclusion: The CSF India-ink/hematoxylin-eosin staining is critical to diagnose.