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Normal and stenotic renal arteries: experimental balloon-expandable intraluminal stenting
Authors:Palmaz  JC; Kopp  DT; Hayashi  H; Schatz  RA; Hunter  G; Tio  FO; Garcia  O; Alvarado  R; Rees  C; Thomas  SC
Abstract:Elastic recoil of the vessel wall is a common cause of failure of percutaneous transluminal angioplasty in renal arteries. To oppose such recoil, balloon-expandable metal stents were implanted in artificially stenotic renal arteries in pigs and normal renal arteries in dogs and pigs. The stents were then examined angiographically and histologically at regular intervals. All stents were completely covered with endothelialized neointima in 3 weeks. There was no difference in intimal thickness between the stenotic and nonstenotic renal arteries. A large stent diameter and a large open or nonmetal surface may cause less intimal hyperplasia, but nonturbulent, fast arterial flow is probably the most important factor in ensuring long-term patency of the vessel.
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