| 贝那普利氯沙坦对原发性高血压伴胰岛素抵抗及高尿酸血症的治疗 |
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| 引用本文： | 郑琼,张道进,陈晓健.贝那普利氯沙坦对原发性高血压伴胰岛素抵抗及高尿酸血症的治疗[J].吉林医学,2011(6):1066-1067. |
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| 作者姓名： | 郑琼 张道进 陈晓健 |
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| 作者单位： | 广东省江门市第二人民医院; |
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| 摘 要： | 目的:观察贝那普利与氯沙坦对原发性高血压合并胰岛素抵抗(IR)以及高尿酸血症(Hu)患者相关参数的影响。方法:60例原发性高血压合并胰岛素抵抗以及高尿酸血症患者分成贝那普利治疗组(A组)、氯沙坦治疗组(B组),疗程8周,观察治疗前后两组间血压、空腹血糖、血清胰岛素水平、血尿酸、胰岛素敏感指数(ISI)的变化。结果:两组治疗前后收缩压、舒张压、空腹血清胰岛素水平皆有显著下降,胰岛素敏感指数(ISI)与治疗前相比有明显上升,氯沙坦组血尿酸较治疗前有明显下降,而贝那普利组比较,差异无统计学意义(P>0.05)。结论:贝那普利与氯沙坦对于合并有胰岛素抵抗以及高尿酸血症的原发性高血压患者皆有降压和改善IR作用,氯沙坦还具有降低血尿酸的作用。
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| 关 键 词： | 高血压 胰岛素抵抗 高尿酸血症 贝那普利 氯沙坦 |
Treatment of Essential Hypertension in Patients with Insulin Resistance and High Uric Acid by Benazepril and Valsartan |
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| ZHENG Qiong,ZHANG Dao-jin,CHEN Xiao-jian.Treatment of Essential Hypertension in Patients with Insulin Resistance and High Uric Acid by Benazepril and Valsartan[J].Jilin Medical Journal,2011(6):1066-1067. |
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| Authors: | ZHENG Qiong ZHANG Dao-jin CHEN Xiao-jian |
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| Institution: | (No.2 People’s Hospital of Jiangmen City Guangdong Province,Guangdong Jiangmen 529000) |
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| Abstract: | Objective To study the effects of Benazepril and Valsartan on essential hypertension patients with insulin resistance(IR)and high uric acid(HU).Methods 60 patients with IR and HU were divided into two groups-Beamzepril treatment group(group A)and Valsaran treatment group(group B).Before treatment and after 8 weeks of treatment,blood pressure,plasma levels of glucose,insulin,uric acid,insulin sensitive index(ISI)were detected.Results Before and after treatment blood pressure,fasting serum insulin level had s... |
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| Keywords: | Essential hypertension Insulin resistance High Uric Acid Benazepril Valsartan |
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