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八味通络颗粒对扩张型心肌病患者血浆BNP的影响
引用本文:牛天福,李娟,刘朋云,祁慧霞,耿强,王建平,杨小燕. 八味通络颗粒对扩张型心肌病患者血浆BNP的影响[J]. 山西中医, 2010, 26(4): 44-46
作者姓名:牛天福  李娟  刘朋云  祁慧霞  耿强  王建平  杨小燕
作者单位:山西省中医院,太原,030012
摘    要:目的:观察八味通络颗粒联合常规西药治疗扩张型心肌病的安全性及对血浆脑利钠肽(BNP)的影响。方法:选择60例扩张型心肌病患者,随机分为两组(各30例),治疗组予常规西药加中药制剂八味通络颗粒,对照组使用常规西药加八味通络颗粒模拟剂。疗程均为8周。观察治疗前后LVEDV、LVESV、LVEF、FS、E/A及血浆脑利钠肽(BNP)的变化情况。结果:血浆脑利钠肽水平随心功能的加重而升高,且在Ⅱ级与Ⅲ级、Ⅱ级与Ⅳ级之间有显著性差异(P〈0.01).血浆脑利钠肽治疗组较对照组疗后无显著性差异,但组内较疗前均有很大改善。结论:八味通络颗粒联合西药较单纯西药治疗扩张型心肌病能够起到增效减毒的作用,改善心功能,缓解症状,未见不良反应。

关 键 词:扩张型心肌病  八味通络颗粒  脑利钠肽  中西医结合疗法  BNP

The Effect of Granule of Eight Herbs for Clearing out Collaterals on BNP in Dilated Cardiomyopathy
NIU Tian-fu,LI Juan,LIU Peng-yun,et al.. The Effect of Granule of Eight Herbs for Clearing out Collaterals on BNP in Dilated Cardiomyopathy[J]. Shanxi Journal of Traditional Chinese Medicine, 2010, 26(4): 44-46
Authors:NIU Tian-fu  LI Juan  LIU Peng-yun  et al.
Affiliation:NIU Tian-fu,LI Juan,LIU Peng-yun,et al.(Shanxi TCM Hospital,Taiyuan,030012,China)
Abstract:Objective: To observe the clinical efficacy and safety of Granule of Eight Herbs for Clearing out Collaterals combined with conventional western medicine on dilated cardiomyopathy and brain natriuretic peptide(BNP) in plasma.Method: 60 cases with dilated cardiomyopathy were randomly divided into treatment group(30 cases) and control group(30 cases).The cases in treatment group were treated with conventional western medicine and Granule of Eight Herbs for Clearing out Collaterals,and the ones in control grou...
Keywords:BNP
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