| 瘦素与慢性肾功能衰竭 |
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| 引用本文： | 付莉,叶本兰. 瘦素与慢性肾功能衰竭[J]. 临床和实验医学杂志, 2008, 7(1): 158-159 |
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| 作者姓名： | 付莉 叶本兰 |
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| 作者单位： | 1. 厦门大学医学院2004级,福建,厦门,361005
2. 厦门大学医学院,生理学教研室,福建,厦门,361005 |
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| 摘 要： | 瘦素是一种由肥胖基因（Obgene）编码的分子量为16.7kDa的多肽类激素,具有降低食欲、增加能量消耗等重要生理作用。瘦素与肾脏的关系密切,肾脏是瘦素的主要清除器官,同时瘦素又可对肾脏功能产生直接作用,影响慢性肾功能衰竭患者的疾病进程。因此,研究者希望通过调节血清中瘦素水平,达到缓解慢性肾功能衰竭进程的目的。
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| 关 键 词： | 瘦素 肾脏 慢性肾功能衰竭 |
| 收稿时间： | 2007-10-28 |
| 修稿时间： | 2007-10-28 |
Leptin and Chronic Renal Failure |
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| FU Li,YE Ben-lan. Leptin and Chronic Renal Failure[J]. Journal of Clinical and Experimental Medicine, 2008, 7(1): 158-159 |
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| Authors: | FU Li YE Ben-lan |
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| Affiliation: | FU Li,YE Ben-lan(1 Grad of 2004 ,2 Department of Physiology,Medical College of Xiamen University,Xiamen Fujian 361005,China) |
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| Abstract: | Leptin is a kind of polypeptide hormone coded by Ob-gene.It performs important functions in regulating energy balance,such as depressing appetite,enhancing caloric consumption,et al.Leptin has a close relationship with kidney,for it is metabolized and eliminated via kidney.On the other hand,leptin effects on kidney functions directly,influencing the process of chronic renal failure.Therefore,it is expectable to slow down the process of chronic renal failure by control leptin level in serum.In this paper,we summarized the researches on the relationship between leptin and kidney function. |
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| Keywords: | Leptin Kidney Chronic renal failure |
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