冠脉支架ZetaTM和DriverR的临床应用观察

 目的观察冠脉支架Multi-Llink RX ZetaTM和DriveR的特点、临床应用的安全性及其短期随访结果.方法分析经选择性冠状动脉造影(Coronary angiography,CAG)证实为管腔狭窄面积＞75%的冠心病(Coronary heart disease,CHD)患者87例,46例冠状动脉内置入Multi-Llink RX ZetaTM支架,共置入支架47只;41例冠状动脉内置入DriverR支架,共置入支架41只,观察支架术后疗效和6个月内临床心脏事件(Major adverse cardiac events,MACE)发生率以及再狭窄率.结果两组手术成功率均为100%.Multi-Llink RX ZetaTM支架组,血管扭曲病变及长病变占89.5%,6个月MACE发生率为2.2%,再狭窄率为12.6%;DriverR支架组,扭曲病变及长病变占87.8%,分叉病变占46.7%,其中,直接置入支架4个,6个月MACE发生率为2.4%,再狭窄率为12.2%.结论两组手术成功率高,治疗扭曲病变及长病变疗效好,MACE发生率和6个月再狭窄率均较低;Multi-Llink RX ZetaTM支架具有良好的跟踪性和高穿过性,DriverR支架具有可弯曲性好、支撑力好、侧孔大、易到位等优点,直接置入成功率高,对边支血管影响小,适用于分叉病变.

Six-month follow-up of implantation with ZetaTM and DriverR stents in coronary artery disease patients

Objective To investigate the characteristics,clinical safety and short-term follow-up outcome of Multi-Link Rx Zeta TM and Driver R stents.Methods Eighty-seven patients with coronary artery stenosis area exceeding 75% confirmed by coronary angiography were enrolled in this study. Forty-six Zeta TM coronary stents were implanted in forty-six coronary artery segments, and forty-one Driver R stents were implanted in forty-one coronary artery segments. Six-month follow-up study was completed in all cases. The therapeutic effect, major adverse cardiac events (MACE) and restenosis were investigated.Results Successful procedure rates were 100% in both groups. Tortuous and long lesions occupied 89.5% and 87.8% in Multi-Link Rx Zeta TM stent group and Driver stent group, respectively;the rates of 6-month MACE were 2.2% and 2.4%;in-stent restenosis rates were 12.6% and 12.2%. Bifurcation lesion were accounted for 46.7% in Driver R group.Conclusion Multi-Link Rt Zeta TM stent is more capatle of tracking and crossing, and Driver R stent is more suitable for bifurcation lesions that require flexibility and supporting. The result of this study provides a better choice of stents for implantation when the physician is confronted with complicated coronary lesions.