联合用药治疗沙眼衣原体宫颈炎的探讨

目的探讨沙眼衣原体(chlamydiatrachomatis,CT)宫颈炎有效的治疗方法及效果。方法选择2001年1月至2003年12月在我院妇科门诊就诊的宫颈炎患者412例,年龄21～54岁,采用无菌标本收集管收集宫颈口的白带,送至检验科CT DNA检测,采用荧光PCR检测试剂严格按试剂盒说明书操作进行CT的检测,对口服阿奇霉素及宫颈局部红霉素治疗进行观察。实验组口服阿奇霉素1g,3d后再服1g,同时宫颈用红霉素粉剂置宫颈管处15min;对照组仅口服红霉素200mg/d,每日2次,口服14d。结果实验组的治疗效果明显好于对照组,实验组对照组治疗效果相差非常显著(P<0.01),说明CT感染者如伴有宫颈糜烂则应在治疗后或同时进行宫颈的微波治疗,可达到良好的治疗效果。结论对于宫颈衣原体感染,口服阿奇霉素及宫颈局部红霉素治疗结合效果较好。

Combined medication in treatment of cervicitis caused by chlamydia trachomatis

Objective To investigate the effective therapy of cervicitis caused by chlamydia trachomatis. Methods A total of 412 patients admitted by our department from Jan 2001 to Dec 2003, aged from 21 to 54 years old, were studied. Leucorrhea from the cervix was collected and examined for CT-DNA by PCR. The experiment group administrated one-gram miramycin every three days and meanwhile applied abomacetin to the cervix for 15 min each time. The control group only took miramycin of 200 mg/d, twice a day for 14 d. The therapeutic effects of two groups were observed. Results The therapeutic effects in the experiment group was better than those of the control group (P<0.01). Conclusion Combined medication of miramycin and abomacetin is an effective method in the treatment of cervicitis caused by chlamydia trachomatis.