| 健择在难治性非霍奇金淋巴瘤治疗中的应用研究 |
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| 引用本文： | 黄日平,马树东,盛信秀,罗荣城,蔡红兵.健择在难治性非霍奇金淋巴瘤治疗中的应用研究[J].肿瘤防治研究,2004,31(3):166-167. |
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| 作者姓名： | 黄日平 马树东 盛信秀 罗荣城 蔡红兵 |
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| 作者单位： | 510515,广州,第一军医大学南方医院肿瘤科 |
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| 摘 要： | 目的 观察健择联合顺铂、强的松治疗难治性非霍奇金淋巴瘤的近期疗效。方法 健择10 0 0mg/m2 ,静滴 ,d1,8;顺铂 2 5mg/m2 ,静滴 ,d1～ 3 ;强的松 6 0mg/m2 ,口服 ,d1～ 5。以 3～ 4周为 1周期 ,每例患者至少连用 3个周期。结果 全组 10例病人中 ,CR 2例 ,PR 5例 ,总有效率 70 %。 4例具有B类症状患者中 ,2例症状消失 ,1例明显改善 ,1例无改善。毒副反应主要是轻度的胃肠道反应和少数患者出现Ⅲ级以上骨髓抑制。结论 健择联合顺铂、强的松治疗难治性非霍奇金淋巴瘤有较好的近期疗效 ,其毒副反应可耐受 ,是值得临床进一步验证的补救性化疗方案。
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| 关 键 词： | 非霍奇金淋巴瘤 健择 化疗 |
| 文章编号： | 1000-8578(2004)03-0166-02 |
| 收稿时间： | 2003-2-18 |
| 修稿时间： | 2003-4-2 |
Clinical Applications of Gemcitabine in the Treatment of Refractory Non-Hodgkin's Lymphoma |
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| HUANG Ri-ping,MA Shu-dong,SHEN Xin-xiu,LUO Rong-cheng,CAI Hong-bing.Clinical Applications of Gemcitabine in the Treatment of Refractory Non-Hodgkin''''s Lymphoma[J].Cancer Research on Prevention and Treatment,2004,31(3):166-167. |
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| Authors: | HUANG Ri-ping MA Shu-dong SHEN Xin-xiu LUO Rong-cheng CAI Hong-bing |
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| Institution: | HUANG Ri-ping,MA Shu-dong,SHEN Xin-xiu,LUO Rong-cheng,CAI Hong-bing Department of Oncology,Nanfang Hospital,The First Medical Military University,Guangzhou 510515,China |
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| Abstract: | Objective To study the effects of gemcitabine combined with cisplatine and predinisone in the treatment of refractory Non-Hodgkin s Lymphoma(NHL). Methods 10 patients with refractory NHL were treated with gemcitabine, 1000mg/m 2,VD,d_ 1,8;cisplatine, 25mg/m 2,VD,d_ 1～3; and prednisone, 60mg/m 2, po,d_ 1～5; every cycle(3～4 weeks). All patients received at least three cycles of chemotherapy. Results There were 2 cases of CR, 5 cases of PR and the total response rate was 70%. Of the 4 patients who suffe... |
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| Keywords: | Non-Hodgkin's Lymphoma Gemcitabine Chemtherapy |
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