三拗片联合西药治疗急性支气管炎风寒袭肺证临床研究

目的：观察三拗片联合西药治疗急性支气管炎风寒袭肺证的临床疗效。方法：选取110例急性支气管炎风寒袭肺证患者，按照随机数字表法分为三拗片组和对照组，每组55例。对照组剔除1例，最终纳入研究54例。对照组给予注射用头孢曲松钠、复方福尔可定口服溶液治疗，三拗片组在对照组基础上给予三拗片治疗。2组均治疗7 d。比较2组临床疗效，咳嗽、咳痰消失时间，白细胞计数、中性粒细胞百分比、血沉水平，以及不良反应发生率。结果：治疗后，三拗片组总有效率98.18%，高于对照组85.19%，差异有统计学意义（P＜0.05）。三拗片组咳嗽消失、咳痰消失时间均短于对照组，差异均有统计学意义（P＜0.05）。治疗后，2组白细胞计数、中性粒细胞百分比、血沉水平均较治疗前降低，三拗片组白细胞计数、中性粒细胞百分比、血沉水平均低于对照组，差异均有统计学意义（P＜0.05）。治疗期间，三拗片组不良反应发生率3.64%，与对照组5.56%比较，差异无统计学意义（P＞0.05）。结论：三拗片联合西药治疗急性支气管炎风寒袭肺证临床疗效显著，可有效缓解临床症状，抑制机体炎症反应，且安全性好。

Clinical Study on San''ao Tablets Combined with Western Medicine for AcuteBronchitis with Syndrome of Wind-Cold Attacking the Lung

Abstract： Objective： To observe the clinical effect of the therapy of San''ao Tablets combined withwestern medicine on acute bronchitis with syndrome of wind-cold attacking the lung. Methods：A total of110 cases of patients with acute bronchitis with syndrome of wind-cold attacking the lung were selectedand divided into the San''ao Tablets group and the control group according to random number table method，with 55 cases in each group. One case was excluded from the control group，and eventually 54 cases wereincluded in it. The control group was treated with Ceftriaxone for Injection and Compound Forcodine OralSolution，and the San''ao Tablets group was additionally treated with San''ao Tablets based on the treatmentof the control group. Both groups were treated for 7 days. The clinical effects，disappearance time of coughand expectoration，white blood cell count，neutrophil percentage，erythrocyte sedimentation rates，andthe incidence of adverse reactions were compared between the two groups. Results：After treatment，thetotal effective rate was 98.18% in the San''ao Tablets group， higher than that of 85.19% in the controlgroup，the difference being significant (P＜0.05). The disappearance time of cough and expectoration in theSan''ao Tablets group were shorter than those in the control group，differences being significant (P＜0.05). After treatment ， the white blood cell count ， neutrophil percentage ， and erythrocyte sedimentationrate (ESR) levels in the two groups were decreased when compared with those before treatment，and thewhite blood cell count，neutrophil percentage，and ESR level in the San''ao Tablets group were lower thanthose in the control group， differences being significant (P＜0.05). During treatment， the incidence ofadverse reactions was 3.64% in the San''ao Tablets group， compared with that of 5.56% in the controlgroup， there was no significant in the difference (P＞0.05). Conclusion： The therapy of San''ao Tabletscombined with western medicine has a significant therapeutic effect on acute bronchitis with syndrome ofwind-cold attacking the lung， which can effectively relieve clinical symptoms， inhibit the bodyinflammatory responses，and has great safety.