温针灸对中风后遗症患者血清炎症因子的影响

目的:探讨温针灸对中风后遗症患者疗效及对血清炎症因子水平的影响。方法:将80例患者随机分为观察组和对照组,对照组39例采用常规西医治疗,观察组41例采用温针灸治疗,观察对比两组临床疗效、中医证候积分、美国国立卫生院神经功能缺损(NIHSS)评分、肢体运动功能评分(FMA)、Barthel指数、血清同型半胱氨酸(Hcy)、一氧化氮(NO)、中枢神经特异性蛋白(S100-β)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白介素-6(IL-6)水平等。结果:治疗后观察组总有效率和中医证候积分显著高于对照组(P<0.05); 观察组NIHSS评分、血清Hcy、NO、TNF-α、S100-β、CRP、IL-6水平均较对照组显著降低(P<0.05); FMA评分、Barthel指数均较对照组显著升高(P<0.05)。结论:温针灸对中风后遗症有较好的疗效,能有效降低血清Hcy、TNF-α及NO水平,抑制炎症反应,改善患者神经功能,有助于患者恢复。

Effects of warm acupuncture and moxibustion on serum inflammatory factor in patients with stroke sequelae

Objective:To investigate the effect of warm acupuncture and moxibustion on serum inflammatory factor levels in patients with stroke sequelae and to observe the clinical efficacy.Methods:80 patients were randomly divided into observation group and control group,39 cases in the control group were treated with conventional western medicine,and 41 cases in the observation group were treated with warm acupuncture and moxibustion.Clinical curative effect,TCM syndrome score,NIHSS score,FMA score,Barthel index,serum homocysteine(Hcy),nitric oxide(NO),central nervous system specific protein(S100-β),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),interleukin-6(IL-6)levels were compared between the two groups.Results:After treatment,the total effective rate and TCM syndrome scores of the observation group were significantly higher than those of the control group(P<0.05); NIHSS score,serum Hcy,NO,TNF-α,S100-β,CRP,IL-6 levels in observation group were higher than those of the control group significantly decreased(P<0.05); FMA score and Barthel index were significantly higher than those in the control group(P<0.05).Conclusion:Warm acupuncture and moxibustion has a good curative effect,can effectively reduce serum Hcy,TNF-α and NO levels,reduce inflammatory response,enhance patients' neurological function,and help patients recover.