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Repressed ileal artery aneurysms in Churg-Strauss syndrome following combination treatment with glucocorticoid and cyclophosphamide
Authors:Akira Yamasaki  Katsuyuki Tomita  Yoshihiro Fujii  Yasuyuki Hasegawa  Masanari Watanabe  Hiroyuki Sano  Ryota Okazaki  Yasufumi Ouchi  Seiichi Nakamura  Eiji Shimizu
Affiliation:(1) Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, 36-1 Nishi-machi, Yonago Tottori, 683-8504, Japan;(2) Department of Radiology, Tottori University, 36-1 Nishi-machi, Yonago Tottori, 683-8504, Japan;(3) Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, Tottori University, 36-1 Nishi-machi, Yonago Tottori, 683-8504, Japan
Abstract:Churg-Strauss syndrome (CSS) is a systemic small-vessel vasculitis characterized by asthma and eosinophilia. We report a case of CSS complicated by multiple aneurysms in the small intestine. A 57-year-old man was admitted to our hospital with fever and blood eosinophilila. During admission, aneurysms in his small intestine ruptured and partial resection of the small intestine was required. After combination therapy of glucocorticoid (GC) and cyclophosphamide (CYC) for 6 months, aneurysms in the small intestine disappeared. The gastrointestinal involvements usually result in poor prognosis in CSS. However, combination therapy of GC and CYC might be effective for remission of aneurysms caused by small vessel vasculitis.
Keywords:Churg-Strauss syndrome  Aneurysms  Cyclophosphamide  Angiography
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