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6种尼莫地平片剂的溶出度比较
引用本文:范金红,高尚伟,田作明,高桂萍,金丽娟.6种尼莫地平片剂的溶出度比较[J].中国药房,2003,14(11):684-685.
作者姓名:范金红  高尚伟  田作明  高桂萍  金丽娟
作者单位:1. 辽宁省人民医院药剂科,沈阳市,110015
2. 辽宁省医药贸易有限公司,沈阳市,110003
摘    要:目的 :考察6种尼莫地平片剂的内在质量。方法 :按照《中国药典》的有关规定 ,分别测定6种样品在乙醇、人工胃液、人工肠液3种溶出介质中的溶出度。结果 :国产尼莫地平分散片的溶出度虽不及进口产品 ,但明显高于其它国产品牌。结论 :a片由于采用了先进的固体分散技术 ,有效地提高了溶出速率 ,使之在质量上与国内其它受试品相比占优势 ;在价格上与进口产品相比占优势

关 键 词:尼莫地平  片剂  溶出度
文章编号:1001-0408(2003)11-0684-02
修稿时间:2002年8月23日

Comparison of Dissolubility Among Six Kinds of Nimodipine Tablets
FAN Jinhong,GAO Shangwei,TIAN Zuoming,GAO Guiping.Comparison of Dissolubility Among Six Kinds of Nimodipine Tablets[J].China Pharmacy,2003,14(11):684-685.
Authors:FAN Jinhong  GAO Shangwei  TIAN Zuoming  GAO Guiping
Abstract:OBJECTIVE:To compare the qualities of six kinds of Nimodipine tablet in terms of dissolubility METHODS:According to Appendix of Chp(2000),the dissolubilities of six kinds of Nimodipine tablet in ethanol,artificial gastric juice and artificial intestinal juice were determined respectively RESULTS:The dissolubility of domestic dispersion tablets was not as good as that of imported products but was obviously superior to that of other domestic products CONCLUSION:Owing to the use of advanced solid dispersion technic,Nidaer tablet is better than other domestic Nimodipine tablets in quality and its price is lower than that of similar imported product
Keywords:Nimodipine  tablet  dissolubility  
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