18F-FDG PET/CT对老年结肠癌的诊断价值

目的 分析18F-氟代脱氧葡萄糖（18F-fluorode-oxyglucose，18F-FDG）正电子发射计算机体层显像（positron emission tomography and computed tomography，PET/CT）对老年结肠癌的诊断价值。方法 回顾性选取2021年1月至2022年12月景德镇市中医医院收治的102例结肠癌患者，分析患者18F-FDG PET/CT显像与临床特征的关系及诊断价值。结果 典型结肠癌18F-FDG PET/CT显像主要集中在升结肠、横结肠、降结肠、乙状结肠4个部位，每个部位的糖代谢升高，肠壁增厚，标准摄取值（standardized uptake value，SUV）增高。不同病灶垂直厚度、性别、淋巴结转移的结肠癌患者的SUV比较差异均有统计学意义（P<0.05）。SUV与病灶垂直厚度、淋巴结转移呈正相关（P<0.05）。受试者操作特征曲线结果显示，18F-FDG PET/CT诊断结肠癌淋巴结转移的曲线下面积为0.993，敏感度为97.2%，特异性为100%。结论 18F-FDG PET/CT用于老年结肠癌患者的诊断具有较高的临床应用价值。

Diagnostic value of 18F-FDG PET/CT in elderly patients with colon cancer

Objective To analyze diagnostic value of 18F-fluorode-oxyglucose (18F-FDG) positron emission tomography and computed tomography (PET/CT) in elderly patients with colon cancer. Methods A total of 102 patients with colon cancer admitted to Jingdezhen Hospital of Traditional Chinese Medicine from January 2021 to December 2022 were retrospectively selected to analyze the relationship between 18F-FDG PET/CT imaging and clinical features and its diagnostic value. Results The typical 18F-FDG PET/CT imaging of colon cancer was mainly concentrated in ascending colon, transverse colon, descending colon, and sigmoid colon. The glucose metabolism of each part increased, the intestinal wall thickened, and standardized uptake value (SUV) increased. There were statistically significant differences in SUV among colon cancer patients with different vertical thickness of the lesion, gender and lymph node metastasis (P<0.05). SUV was positively correlated with vertical thickness of the lesion and lymph node metastasis (P<0.05). Receiver operating characteristic curve results showed that the area under the curve of 18F-FDG PET/CT for diagnosis of colon cancer lymph node metastasis was 0.993, the sensitivity was 97.2%, and the specificity was 100%. Conclusion 18F-FDG PET/CT for the diagnosis of elderly patients with colon cancer has a high clinical application value.