| 环状RNA与动脉粥样硬化的相关性及中药调控研究进展 |
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| 引用本文： | 黄炳谕,郭志焱,刘莹. 环状RNA与动脉粥样硬化的相关性及中药调控研究进展[J]. 中国动脉硬化杂志, 2024, 32(2): 164-170 |
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| 作者姓名： | 黄炳谕 郭志焱 刘莹 |
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| 作者单位： | 广西医科大学第一附属医院康复医学科,广西南宁市530021 |
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| 基金项目： | 国家自然科学基金项目(81901394) |
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| 摘 要： | 环状RNA是一种新兴的非编码RNA,与动脉粥样硬化(As)的脂质沉积、炎症反应、细胞凋亡、增殖和修复等过程密切相关,影响As的发生发展。传统中药在防治As中具有重要的学术价值,其调控机制尚未得到全面总结。文章对环状RNA与As中的脂质沉积、炎症反应和巨噬细胞的联系进行了综述,总结回顾环状RNA与As相关性及中药调控研究进展。
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| 关 键 词： | 环状RNA 动脉粥样硬化 中药 |
| 收稿时间： | 2023-08-16 |
| 修稿时间： | 2023-09-30 |
Research progress on the role of circRNA in atherosclerosis and the regulation of traditional Chinese medicine |
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| HUANG Bingyu,GUO Zhiyan,LIU Ying. Research progress on the role of circRNA in atherosclerosis and the regulation of traditional Chinese medicine[J]. Chinese Journal of Arteriosclerosis, 2024, 32(2): 164-170 |
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| Authors: | HUANG Bingyu GUO Zhiyan LIU Ying |
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| Affiliation: | Department of Rehabilitation Medicine, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China |
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| Abstract: | Circular RNA (circRNA), an emerging non-coding RNA, is closely related to the processes of lipid deposition, inflammatory response, apoptosis, proliferation and repair in atherosclerosis (As), and affects the development of As. Traditional Chinese medicine (TCM) has an important academic value in the prevention and treatment of As, and its regulatory mechanism has not been comprehensively summarized. This paper reviewed the association of circRNA with lipid deposition, inflammatory response and macrophage in As, and summarized the research progress of the correlation between circRNA and atherosclerosis and the regulation of traditional Chinese medicine. |
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| Keywords: | circRNA atherosclerosis traditional Chinese medicine |
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