内镜下食管曲张静脉套扎治疗老年性肝硬化出血合并门静脉血栓42例临床分析

目的食管曲张静脉套扎治疗老年性肝硬化出血合并门静脉血栓后对肝功能分级及临床指标的影响。 方法回顾分析上海交通大学附属瑞金医院北院2013年1月至2018年1月收治肝硬化致食管静脉曲张上消化道出血合并门静脉血栓42例患者，比较食管曲张静脉套扎治疗前后相关实验室检查数值变化及治疗前后Child分级的变化。 结果治疗前后pro-ALB、AST、ALB、TBIL、Scr、WBC、Hb、PLT、PT、INR数值稍有变化，但差异均无统计学意义。提示治疗前后部分生化、血常规、凝血功能无明显影响。治疗前后Child分级(A级19例，B级19例，C级4例)较治疗前(A级19例，B级22例，C级1例)也无明显变化。 结论食管曲张静脉套扎治疗老年性肝硬化出血合并门静脉血栓短期止血效果较好，其安全性较高，耐受可，对肝功能、凝血功能等影响小。

Clinical analysis of 42 cases of endoscopic esophageal variceal ligation in the treatment of senile cirrhosis hemorrhage complicated with portal vein thrombosis

ObjectiveTo explore the effects of esophageal variceal ligation on hepatic function grading and clinical indexes in senile cirrhosis hemorrhage complicated with portal vein thrombosis. MethodsA total of 42 cases of esophageal varices hemorrhage associated with portal vein thrombosis caused by liver cirrhosis in Ruijin Hospital North Shanghai Jiaotong University School of Medicine from January 2013 to January 2018 were analyzed retrospectively.The changes of the relevant laboratory test values and Child grading which before and after the treatment of esophageal variceal ligation were compared. ResultsAlthough the values of pro-ALB, AST, ALB, TBIL, Scr, WBC, Hb, PLT, PTand INR were slightly changed before and after treatment, there were no statistically significant differences.It was suggested that the results of biochemical tests, blood testsand coagulation function tests had no obvious changes before and after treatment.The Child grading had no obvious change before and after treatment(19 cases were of grade A, 19 cases were of grade B, 4 cases were of grade C before treatment and 19 cases were of grade A, 22 cases were of grade B, 1 case was of grade C after treatment). ConclusionEsophageal variceal ligation in the treatment of senile cirrhosis hemorrhage complicated with portal vein thrombosis has a good short-term hemostasis effect, which is safe, tolerable, and has little effect on liver function and coagulation function.